Neo-clerodane diterpenoids from Teucrium polium

被引：31
|
作者：
Bedir, E
Tasdemir, D
Çalis, I [1 ]
Zerbe, O
Sticher, O
机构：
[1] Hacettepe Univ, Fac Pharm, Dept Pharmacognosy, TR-06100 Ankara, Turkey
[2] Swiss Fed Inst Technol, Dept Pharm, CH-8057 Zurich, Switzerland
来源：
PHYTOCHEMISTRY | 1999年 / 51卷 / 07期
关键词：
Teucrium polium; Lamiaceae; diterpenoids; neo-clerodane derivative; teulolins A; B;
D O I：
10.1016/S0031-9422(99)00052-7
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Two new neo-clerodane type diterpenoids, teulolin A (15,16-epoxy-6 beta,7 beta,18,19-tetrahydroxy-neo-cleroda-3(4),13(16),14-trien-20,12(S)-olide, 1) and teulolin B (15,16-epoxy-3 alpha, 6 beta, 7 beta, 18, 19-tetrahydroxy-neo-cleroda-4(18),13(16),14-trien-20,12(S)-olide, 2) were isolated from the aerial parts of Teucrium polium. The structures of 1-2 were proposed on the basis of extensive NMR experiments and molecular modeling studies. (C) 1999 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：921 / 925
页数：5
相关论文
共 50 条
  • [1] neo-Clerodane diterpenoids from Teucrium alyssifolium
    Topcu, G
    Eris, C
    Ulubelen, A
    JOURNAL OF NATURAL PRODUCTS, 1997, 60 (10): : 1045 - 1047
  • [2] Neo-clerodane diterpenoids from Teucrium sandrasicum
    delaTorre, MC
    Rodriguez, B
    Bruno, M
    Fazio, C
    Baser, KHC
    Duman, H
    PHYTOCHEMISTRY, 1997, 45 (08) : 1653 - 1662
  • [3] NEO-CLERODANE DITERPENOIDS FROM TEUCRIUM-MICROPODIOIDES
    DELATORRE, MC
    RODRIGUEZ, B
    BRUNO, M
    SAVONA, G
    PIOZZI, F
    SERVETTAZ, O
    PHYTOCHEMISTRY, 1988, 27 (01) : 213 - 216
  • [4] Neo-clerodane diterpenoids from three species of Teucrium
    Rodriguez, B
    delaTorre, MC
    Bruno, M
    Piozzi, F
    Vassallo, N
    Ciriminna, R
    Servettaz, O
    PHYTOCHEMISTRY, 1996, 43 (02) : 435 - 438
  • [5] NEO-CLERODANE DITERPENOIDS FROM TEUCRIUM-CANADENSE
    BRUNO, M
    PIOZZI, F
    SAVONA, G
    DELATORRE, MC
    RODRIGUEZ, B
    PHYTOCHEMISTRY, 1989, 28 (12) : 3539 - 3541
  • [6] NEO-CLERODANE DITERPENOIDS FROM TEUCRIUM-PYRENAICUM
    GARCIAALVAREZ, MC
    MARCO, JL
    RODRIGUEZ, B
    SAVONA, G
    PIOZZI, F
    PHYTOCHEMISTRY, 1982, 21 (10) : 2559 - 2562
  • [7] A NEO-CLERODANE GLUCOSIDE AND NEO-CLERODANE DITERPENOIDS FROM TEUCRIUM-FLAVUM SUBSP GLAUCUM
    SAVONA, G
    PIOZZI, F
    SERVETTAZ, O
    RODRIGUEZ, B
    FERNANDEZGADEA, F
    MARTINLOMAS, M
    PHYTOCHEMISTRY, 1984, 23 (04) : 843 - 848
  • [8] NEO-CLERODANE DITERPENOIDS FROM TEUCRIUM-ABUTILOIDES
    DELATORRE, MC
    RODRIGUEZ, B
    PIOZZI, F
    SAVONA, G
    BRUNO, M
    CARREIRAS, MC
    PHYTOCHEMISTRY, 1990, 29 (02) : 579 - 584
  • [9] NEO-CLERODANE DITERPENOIDS FROM TEUCRIUM-KOTSCHYANUM
    SIMOES, F
    RODRIGUEZ, B
    BRUNO, M
    PIOZZI, F
    SAVONA, G
    ARNOLD, NA
    PHYTOCHEMISTRY, 1989, 28 (10) : 2763 - 2768
  • [10] NEO-CLERODANE DITERPENOIDS FROM TEUCRIUM-MASSILIENSE
    SAVONA, G
    BRUNO, M
    PIOZZI, F
    SERVETTAZ, O
    RODRIGUEZ, B
    PHYTOCHEMISTRY, 1984, 23 (04) : 849 - 852
12345