Neo-clerodane diterpenoids from Teucrium polium

被引：31

作者：

Bedir, E

Tasdemir, D

Çalis, I ^{[1
]}

Zerbe, O

Sticher, O

机构：

[1] Hacettepe Univ, Fac Pharm, Dept Pharmacognosy, TR-06100 Ankara, Turkey

[2] Swiss Fed Inst Technol, Dept Pharm, CH-8057 Zurich, Switzerland

来源：

PHYTOCHEMISTRY | 1999年 / 51卷 / 07期

关键词：

Teucrium polium; Lamiaceae; diterpenoids; neo-clerodane derivative; teulolins A; B;

D O I：

10.1016/S0031-9422(99)00052-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Two new neo-clerodane type diterpenoids, teulolin A (15,16-epoxy-6 beta,7 beta,18,19-tetrahydroxy-neo-cleroda-3(4),13(16),14-trien-20,12(S)-olide, 1) and teulolin B (15,16-epoxy-3 alpha, 6 beta, 7 beta, 18, 19-tetrahydroxy-neo-cleroda-4(18),13(16),14-trien-20,12(S)-olide, 2) were isolated from the aerial parts of Teucrium polium. The structures of 1-2 were proposed on the basis of extensive NMR experiments and molecular modeling studies. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：921 / 925

页数：5