Novel Inflammatory Biomarkers in Cardiovascular Therapeutics

被引：1

作者：

Tsigkou, Vicky ^{[1
]}

Siasos, Gerasimos ^{[1
]}

Oikonomou, Evangelos ^{[1
]}

Zaromitidou, Marina ^{[1
]}

Latsios, George ^{[1
]}

Vavuranakis, Manolis ^{[1
]}

Deftereos, Spyridon ^{[1
]}

Cleman, Michael W. ^{[1
]}

Kokkou, Eleni ^{[1
]}

Limberi, Maria ^{[1
]}

Dimitropoulos, Stathis ^{[1
]}

Zografos, Thodoris ^{[1
]}

Marinaki, Smaragdi ^{[1
]}

Stefanadis, Christodoulos ^{[1
,2
]}

Tousoulis, Dimitris ^{[1
]}

机构：

[1] Univ Athens, Sch Med, Hippokrat Hosp, Dept Cardiol 1, GR-11527 Athens, Greece

[2] Emory Univ, Sch Med, Dept Med, Div Cardiol, Atlanta, GA USA

来源：

CURRENT MEDICINAL CHEMISTRY | 2015年 / 22卷 / 23期

关键词：

Atherosclerosis; biomarkers; cardiovascular diseases; coronary artery disease; heart failure; hypertension; inflammation; peripheral artery disease; stroke; C-REACTIVE PROTEIN; PERIPHERAL ARTERIAL-DISEASE; NECROSIS-FACTOR-ALPHA; ANKLE-BRACHIAL INDEX; ACUTE MYOCARDIAL-INFARCTION; SOLUBLE ADHESION MOLECULES; BRAIN NATRIURETIC PEPTIDE; HEART-FAILURE; ATRIAL-FIBRILLATION; OXIDATIVE STRESS;

D O I：

10.2174/0929867322666150429110124

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Inflammation has been established as an important determinant of cardiovascular disease progression. Currently, clinical examination, laboratory and imaging tests are invaluable for the diagnosis, prognosis and disease monitoring. Novel inflammatory biomarkers are also used to better restratify patients in risk groups but their potential to guide treatment decisions and management of patients has not been extensively evaluated. Therefore, in this review article we present the most recent data concerning the use of inflammatory biomarkers in cardiovascular therapeutics.

引用

页码：2773 / 2785

页数：13

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