Personalized Nutrition in Disrupting Cancer - Proceedings From the 2017 American College of Nutrition Annual Meeting

被引:18
作者
Wallace, Taylor C. [1 ,2 ]
Bultman, Scott [3 ]
D'Adamo, Chris [4 ,5 ]
Daniel, Carrie R. [6 ]
Debelius, Justine [7 ]
Ho, Emily [8 ]
Eliassen, Heather [9 ,10 ,11 ]
Lemanne, Dawn [12 ,13 ,14 ]
Mukherjee, Purna [15 ]
Seyfried, Thomas N. [15 ]
Tian, Qiang [16 ]
Vahdat, Linda T. [17 ]
机构
[1] George Mason Univ, Dept Nutr & Food Studies, 10340 Democracy Lane,Suite 306, Fairfax, VA 22030 USA
[2] Think Hlth Grp Inc, Washington, DC USA
[3] Univ N Carolina, Sch Med, Dept Genet, Chapel Hill, NC 27515 USA
[4] Univ Maryland, Sch Med, Ctr Integrat Med, Dept Family & Community Med, College Pk, MD 20742 USA
[5] Univ Maryland, Sch Med, Ctr Integrat Med, Dept Epidemiol & Publ Hlth, College Pk, MD 20742 USA
[6] Univ Texas MD Anderson Canc Ctr, Div Canc Prevent & Populat Sci, Dept Epidemiol, Houston, TX 77030 USA
[7] Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden
[8] Oregon State Univ, Linus Pauling Inst, Sch Biol & Populat Hlth Sci, Moore Family Ctr Whole Grain Foods Nutr & Prevent, Corvallis, OR 97331 USA
[9] Brigham & Womens Hosp, Channing Div Network Med, Boston, MA 02115 USA
[10] Harvard Med Sch, Boston, MA USA
[11] Harvard TH Chan Sch Publ Hlth, Boston, MA USA
[12] Univ Arizona, Dept Med, Tucson, AZ USA
[13] Natl Inst Integrat Med, Melbourne, Vic, Australia
[14] Oregon Integrat Oncol, Ashland, OR USA
[15] Boston Coll, Dept Biol, Chestnut Hill, MA 02167 USA
[16] P4 Med Inst, Inst Syst Biol, Seattle, WA USA
[17] Weill Cornell Med, Weill Cornell Breast Ctr, New York, NY USA
关键词
Cancer; nutrition; American College of Nutrition; scientific statement; HISTONE DEACETYLASE INHIBITORS; BREAST-CANCER; VITAMIN-D; HDAC INHIBITOR; DIETARY RESTRICTION; PLASMA CAROTENOIDS; FTO GENOTYPE; PHASE-II; POOLED ANALYSIS; GUT MICROBIOME;
D O I
10.1080/07315724.2018.1500499
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Cancer is a major public health problem and is the second leading cause of death in the United States and worldwide; nearly one in six deaths are attributable to cancer. Approximately 20% of all cancers diagnosed in the United States are attributable to unhealthy diet, excessive alcohol consumption, physical inactivity, and body fatness. Individual cancers are distinct disease states that are multifactorial in their causation, making them exceedingly cumbersome to study from a nutrition standpoint. Genetic influences are a major piece of the puzzle and personalized nutrition is likely to be most effective in disrupting cancer during all stages. Increasing evidence shows that after a cancer diagnosis, continuing standard dietary recommendations may not be appropriate. This is because powerful dietary interventions such as short-term fasting and carbohydrate restriction can disrupt tumor metabolism, synergizing with standard therapies such as radiation and drug therapy to improve efficacy and ultimately, cancer survival. The importance of identifying dietary interventions cannot be overstated, and the American College of Nutrition's commitment to advancing knowledge and research is evidenced by dedication of the 2017 ACN Annual Meeting to "Disrupting Cancer: The Role of Personalized Nutrition" and this resulting proceedings manuscript, which summarizes the meeting's findings.
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页码:1 / 14
页数:14
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