Cyclic AMP compartments and signaling specificity: Role of cyclic nucleotide phosphodiesterases

被引:93
作者
Conti, Marco [1 ]
Mika, Delphine [1 ]
Richter, Wito [1 ]
机构
[1] Univ Calif San Francisco, Dept Obstet Gynecol & Reprod Sci, Ctr Reprod Sci, Eli & Edythe Broad Ctr Regenerat Med & Stem Cell, San Francisco, CA 94143 USA
关键词
PROTEIN-KINASE; CARDIAC MYOCYTES; STIMULATED PHOSPHODIESTERASE; CAMP COMPARTMENTATION; ADENYLYL-CYCLASE; PHOSPHORYLATION; HEART; LOCALIZATION; ACTIVATION; MEMBRANE;
D O I
10.1085/jgp.201311083
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
引用
收藏
页码:29 / 38
页数:10
相关论文
共 68 条
[1]  
ANANT JS, 1992, J BIOL CHEM, V267, P687
[2]   SPATIALLY RESOLVED DYNAMICS OF CAMP AND PROTEIN KINASE-A SUBUNITS IN APLYSIA SENSORY NEURONS [J].
BACSKAI, BJ ;
HOCHNER, B ;
MAHAUTSMITH, M ;
ADAMS, SR ;
KAANG, BK ;
KANDEL, ER ;
TSIEN, RY .
SCIENCE, 1993, 260 (5105) :222-226
[3]   Phosphodiesterase 4D forms a cAMP diffusion barrier at the apical membrane of the airway epithelium [J].
Barnes, AP ;
Livera, G ;
Huang, PB ;
Sun, CW ;
O'Neal, WK ;
Conti, M ;
Stutts, MJ ;
Milgram, SL .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2005, 280 (09) :7997-8003
[4]   Phosphodiesterase 4D Regulates Baseline Sarcoplasmic Reticulum Ca2+ Release and Cardiac Contractility, Independently of L-Type Ca2+ Current [J].
Beca, Sanja ;
Helli, Peter B. ;
Simpson, Jeremy A. ;
Zhao, Dongling ;
Farman, Gerrie P. ;
Jones, Peter P. ;
Tian, Xixi ;
Wilson, Lindsay S. ;
Ahmad, Faiyaz ;
Chen, S. R. Wayne ;
Movsesian, Matthew A. ;
Manganiello, Vincent ;
Maurice, Donald H. ;
Conti, Marco ;
Backx, Peter H. .
CIRCULATION RESEARCH, 2011, 109 (09) :1024-U119
[5]   Cyclic nucleotide phosphodiesterases: Molecular regulation to clinical use [J].
Bender, Andrew T. ;
Beavo, Joseph A. .
PHARMACOLOGICAL REVIEWS, 2006, 58 (03) :488-520
[6]   PDE4D and PDE4B Function in Distinct Subcellular Compartments in Mouse Embryonic Fibroblasts [J].
Blackman, Brigitte E. ;
Horner, Kathleen ;
Heidmann, Julia ;
Wang, Dan ;
Richter, Wito ;
Rich, Thomas C. ;
Conti, Marco .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2011, 286 (14) :12590-12601
[7]   FRET measurements of intracellular cAMP concentrations and cAMP analog permeability in intact cells [J].
Boerner, Sebastian ;
Schwede, Frank ;
Schlipp, Angela ;
Berisha, Filip ;
Calebiro, Davide ;
Lohse, Martin J. ;
Nikolaev, Viacheslav O. .
NATURE PROTOCOLS, 2011, 6 (04) :427-438
[8]  
BUXTON ILO, 1983, J BIOL CHEM, V258, P233
[9]   Interplay of Palmitoylation and Phosphorylation in the Trafficking and Localization of Phosphodiesterase 10A: Implications for the Treatment of Schizophrenia [J].
Charych, Erik I. ;
Jiang, Li-Xin ;
Lo, Frederick ;
Sullivan, Kelly ;
Brandon, Nicholas J. .
JOURNAL OF NEUROSCIENCE, 2010, 30 (27) :9027-9037
[10]  
Conti M, 2000, PROG NUCLEIC ACID RE, V63, P1