Effect of Labetalol for Treating Patients with Pregnancy-Induced Hypertension: A Systematic Review

被引：0

作者：

Bej, Punyatoya ^{[1
]}

Das, Sambhunath ^{[2
]}

机构：

[1] Rama Med Coll & Res Ctr, Dept Community Med, Hapur, Uttar Pradesh, India

[2] All India Inst Med Sci, Dept Cardiac Anaesthesia, New Delhi, India

来源：

JOURNAL OF THE PRACTICE OF CARDIOVASCULAR SCIENCES | 2022年 / 8卷 / 03期

关键词：

Eclampsia; fetal outcome; labetalol; maternal outcome; nifedipine; preeclampsia; pregnancy-induced hypertension; ORAL NIFEDIPINE; INTRAVENOUS LABETALOL; ANTIHYPERTENSIVE TREATMENT; BLOOD-PRESSURE; HYDRALAZINE; METHYLDOPA; EMERGENCY; TRIAL;

D O I：

10.4103/jpcs.jpcs_69_22

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Pregnancy-induced hypertension (PIH) is one of the main causes of maternal mortality. Many first- and second-line drugs are available to treat the condition. Labetalol lowers blood pressure by blocking both alpha and beta adrenergic receptors. It preserves uteroplacental blood flow efficiently. A systemic review was carried out to find the efficacy and safety of labetalol in the treatment of PIH. Three thousand twenty-six studies were retrieved in 20 years. Finally, 28 studies were selected after applying the review criteria. Twenty-three studies detected that labetalol had superior or similar action compared to other drugs in controlling hypertension in patients with preeclampsia and eclampsia. The systematic review concluded that labetalol is a safe, effective, first-choice of drug with few side effects in treating PIH.

引用

页码：144 / 151

页数：8

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