A simple, rapid, low-cost diagnostic test for sickle cell disease

被引:63
作者
Yang, Xiaoxi [1 ]
Kanter, Julie [2 ,3 ]
Piety, Nathaniel Z. [1 ]
Benton, Melody S. [3 ]
Vignes, Seth M. [1 ]
Shevkoplyas, Sergey S. [1 ]
机构
[1] Tulane Univ, Dept Biomed Engn, New Orleans, LA 70118 USA
[2] Tulane Univ, Sch Med, Dept Pediat, Hematol Oncol Sect, New Orleans, LA 70112 USA
[3] Tulane Univ, Sch Med, Sickle Cell Ctr Southern Louisiana, New Orleans, LA 70112 USA
基金
比尔及梅琳达.盖茨基金会;
关键词
WHOLE-BLOOD SOLUBILITY; HEMOGLOBIN DISORDERS; MECHANISMS; ANEMIA;
D O I
10.1039/c3lc41302k
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
This communication describes a very simple, rapid and inexpensive point-of-care diagnostic test for sickle cell disease (SCD) that can conclusively differentiate between blood samples from normal healthy individuals, sickle cell trait carriers and SCD patients using the characteristic blood stain patterns produced by each sample on paper.
引用
收藏
页码:1464 / 1467
页数:4
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