Chemical Constituents from Stem Bark and Roots of Clausena anisata

被引：42

作者：

Songue, Jules Lobe ^{[1
,2
]}

Kouam ^{[1
]}

Dongo, Etienne ^{[3
]}

Mpondo, Theophile Ngando ^{[1
]}

White, Robert L. ^{[2
]}

机构：

[1] Univ Douala, Dept Chem, Douala, Cameroon

[2] Dalhousie Univ, Dept Chem, Halifax, NS B3H 4R2, Canada

[3] Univ Yaounde I, Dept Organ Chem, Yaounde, Cameroon

来源：

MOLECULES | 2012年 / 17卷 / 11期

基金：

加拿大自然科学与工程研究理事会;

关键词：

Rutaceae; Clausena anisata; stem bark and roots; carbazole alkaloids; peptide derivative; phytosterol; ANTITUMOR-PROMOTING ACTIVITY; CELL-CYCLE ARREST; CARBAZOLE ALKALOIDS; MURRAYA-EUCHRESTIFOLIA; AURANTIAMIDE ACETATE; PIPER-AURANTIACUM; DIPEPTIDE; COUMARINS; GIRINIMBINE; DERIVATIVES;

D O I：

10.3390/molecules171113673

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Phytochemical investigations on the stem bark and roots of the tropical shrub Clausena anisata led to the isolation and characterization three carbazole alkaloids: girinimbine, murrayamine-A and ekeberginine; two peptide derivatives: aurantiamide acetate and N-benzoyl-L-phenylalaninyl-N-benzoyl-L-phenylalaninate; and a mixture of two phytosterols: sitosterol and stigmasterol. The structures of these compounds were established by nuclear magnetic resonance (H-1-NMR, C-13-NMR, COSY, HSQC, HMQC, HMBC and NOESY) spectroscopy and electrospray ionization mass spectrometry (MS).

引用

页码：13673 / 13686

页数：14

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