Novel efficient promoter of the mitochondrial porin, voltage-dependent anion channel (VDAC), in the genome of the Yarrowia lipolytica yeast

被引:2
|
作者
Kulanbaewa, F. F. [1 ]
Sekova, V. Yu. [2 ]
Isakova, E. P. [2 ]
Deryabina, Y. I. [2 ]
Nikolaev, A. V. [3 ]
机构
[1] Mendeleev Univ Chem Technol, Miusskaya Pl 9, Moscow 125190, Russia
[2] Russian Acad Sci, Bach Inst Biochem, Fed Res Ctr Fundamentals Biotechnol, Leninskii Pr 33, Moscow 119071, Russia
[3] Russian Acad Sci, Schmidt Joint Inst Phys Earth, Ul Bolshaya Gruzinskaya 10, Moscow 123810, Russia
基金
俄罗斯基础研究基金会;
关键词
EXPRESSION; VECTORS; CLONING; GENE;
D O I
10.1134/S1607672916050124
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
This article presents the characteristics of the highly inducible promoter of the gene encoding the mitochondrial porin, the voltage-dependent anion channel (VDAC). This promoter is recommended for use in new genetic constructs both in basic research for assessing the adaptive strategy of lower eukaryotes under adverse conditions and in designing new highly competitive transformants producing economically important compounds (proteins, lipids, and organic acids) on its basis.
引用
收藏
页码:349 / 352
页数:4
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