Synthesis of indoles via domino reaction of N-aryl amides and ethyl diazoacetate

被引:110
|
作者
Cui, Sun-Liang [1 ]
Wang, Jing [1 ]
Wang, Yan-Guang [1 ]
机构
[1] Zhejiang Univ, Dept Chem, Hangzhou 310027, Peoples R China
基金
中国国家自然科学基金;
关键词
D O I
10.1021/ja805706r
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A general and concise synthesis of functionalized indoles via domino reaction of N-aryl amides and ethyl diazoacetate has been developed. The methodology offers a great potential for the synthesis of biologically active and naturally occurring indole derivatives.
引用
收藏
页码:13526 / +
页数:3
相关论文
共 50 条
  • [41] Continuous Flow Synthesis of Structurally Symmetrical N-aryl 4-Pyridinones via a Multicomponent Tandem Reaction
    Yang, Qi
    Li, Weiqiang
    Huang, Shuntao
    Li, Jingpeng
    Liu, Teng
    Huang, Chao
    CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 2023, 44 (06):
  • [42] Photo-Induced Construction of N-Aryl Amides by Fe Catalysis
    Mei, Yong-Kang
    Min, Xiang-Ting
    Guo, Shi-Yu
    Liu, Chang-Hui
    Zhang, Xiang-Xin
    Ji, Ding-Wei
    Wan, Boshun
    Chen, Qing-An
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2022, 2022 (14)
  • [43] Intramolecular redox reaction for the synthesis of N-aryl pyrroles catalyzed by Lewis acids
    Du, Hong-Jin
    Zhen, Le
    Wen, Xiaoan
    Xu, Qing-Long
    Sun, Hongbin
    ORGANIC & BIOMOLECULAR CHEMISTRY, 2014, 12 (47) : 9716 - 9719
  • [44] Synthesis of N-Aryl Carbamates from Aryl(TMP)iodonium Salts via C-N Coupling
    Hatton, Joseph
    Stuart, David R.
    ORGANIC LETTERS, 2025,
  • [46] Synthesis and Biological Activities of Some Novel N-Aryl Sulfonyl Trytophanates and N-Aryl Sulfonyl Glutamates
    Li Wen-Ming
    Tan Hai-Zhong
    Wang Jian-Guo
    Li Yong-Hong
    Li Zheng-Ming
    CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 2009, 30 (04): : 728 - 730
  • [47] REACTIONS OF N-ARYL NITROGEN-OXIDES .2. REACTION OF N-ARYL NITRONES WITH OXALYL CHLORIDE
    LIOTTA, D
    BAKER, AD
    GOLDMAN, NL
    ENGEL, R
    JOURNAL OF ORGANIC CHEMISTRY, 1974, 39 (13): : 1975 - 1976
  • [48] NHC-Catalyzed Desymmetrization of N-Aryl Maleimides Leading to the Atroposelective Synthesis of N-Aryl Succinimides
    Barik, Soumen
    Shee, Sayan
    Das, Soumik
    Gonnade, Rajesh G.
    Jindal, Garima
    Mukherjee, Subrata
    Biju, Akkattu T.
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 60 (22) : 12264 - 12268
  • [49] SYNTHESIS AND ANTIARRHYTHMIC ACTIVITY OF N-ARYL ALKYLENEDIAMINES
    ZUBOVICS, Z
    TOLDY, L
    VARRO, A
    RABLOCZKY, G
    KURTHY, M
    DVORTSAK, P
    JERKOVICH, G
    TOMORI, E
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 1986, 21 (05) : 370 - 378
  • [50] Recent developments in the synthesis of N-aryl sulfonamides
    Wu, Huizhen
    Chen, Xuesong
    Sun, Nabo
    Sanchez-Mendoza, Alberto
    SYNTHETIC COMMUNICATIONS, 2021, 51 (15) : 2287 - 2304