Androgen deficiency in older men: Indications, advantages, and pitfalls of testosterone replacement therapy

被引：23
作者：
McGill, John I. [1 ]
Shoskes, Daniel A. [2 ]
Sabanegh, Edmund S. [3 ]
机构：
[1] Univ Hosp Cleveland, Case Med Ctr, Inst Urol, Cleveland, OH 44106 USA
[2] Cleveland Clin, Glickman Urol & Kidney Inst, Cleveland, OH USA
[3] Cleveland Clin, Glickman Urol & Kidney Inst, Dept Urol, Cleveland, OH USA
来源：
CLEVELAND CLINIC JOURNAL OF MEDICINE | 2012年 / 79卷 / 11期
关键词：
LATE-ONSET HYPOGONADISM; LOW SERUM TESTOSTERONE; CLINICAL-PRACTICE GUIDELINE; HORMONE-BINDING GLOBULIN; MIDDLE-AGED MEN; PROSTATE-CANCER; METABOLIC SYNDROME; ERECTILE DYSFUNCTION; SEXUAL FUNCTION; INSULIN-RESISTANCE;
D O I：
10.3949/ccjm.79a.12010
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The decline in testosterone with age has been associated with specific physical changes that affect quality of life and life expectancy, although a cause-and-effect relationship is yet to be established. While female menopause is rapid and well described, "male menopause" or androgen decline in older men is gradual and marked by nonspecific symptoms. This makes diagnosis of true testosterone deficiency and prediction of response to testosterone replacement therapy (TRT) challenging.
引用
收藏
页码：797 / 806
页数：10
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