Highly chemoselective intermolecular cross-benzoin reactions using an ad hoc designed novel N-heterocyclic carbene catalyst

被引：17
|
作者：
Delany, Eoghan G. [1 ]
Connon, Stephen J. [1 ]
机构：
[1] Trinity Coll Dublin, Sch Chem, Trinity Biomed Sci Inst, 152-160 Pearse St, Dublin 2, Ireland
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2018年 / 16卷 / 05期
关键词：
TRIAZOLIUM SALTS; ACYLOIN CONDENSATIONS; BRESLOW INTERMEDIATE; ASYMMETRIC-SYNTHESIS; ALIPHATIC-ALDEHYDES; UMPOLUNG; ORGANOCATALYSIS; GENERATION;
D O I：
10.1039/c7ob03005c
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The design of a novel N-heterocyclic carbene catalyst incorporating a bulky yet highly electron-deficient N-aryl substituent has allowed the development of an efficient protocol for the first highly chemoselective intermolecular benzoin condensations between two non-identical aromatic aldehydes.
引用
收藏
页码：780 / 786
页数：7
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