Highly chemoselective intermolecular cross-benzoin reactions using an ad hoc designed novel N-heterocyclic carbene catalyst

被引：17

作者：

Delany, Eoghan G. ^{[1
]}

Connon, Stephen J. ^{[1
]}

机构：

[1] Trinity Coll Dublin, Sch Chem, Trinity Biomed Sci Inst, 152-160 Pearse St, Dublin 2, Ireland

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2018年 / 16卷 / 05期

关键词：

TRIAZOLIUM SALTS; ACYLOIN CONDENSATIONS; BRESLOW INTERMEDIATE; ASYMMETRIC-SYNTHESIS; ALIPHATIC-ALDEHYDES; UMPOLUNG; ORGANOCATALYSIS; GENERATION;

D O I：

10.1039/c7ob03005c

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The design of a novel N-heterocyclic carbene catalyst incorporating a bulky yet highly electron-deficient N-aryl substituent has allowed the development of an efficient protocol for the first highly chemoselective intermolecular benzoin condensations between two non-identical aromatic aldehydes.

引用

页码：780 / 786

页数：7

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