Synthesis of substituted quinolines from N-aryl-N-(2-alkynyl)toluenesulfonamides via FeCl3-mediated intramolecular cyclization and concomitant detosylation

被引：25

作者：

Roy, B. ^{[1
]}

Ansary, Inul ^{[1
]}

Samanta, Srikanta ^{[1
]}

Majumdar, K. C. ^{[1
]}

机构：

[1] Univ Kalyani, Dept Chem, Kalyani 741235, W Bengal, India

来源：

TETRAHEDRON LETTERS | 2012年 / 53卷 / 38期

关键词：

Sonogashira coupling; N-Aryl-N-(2-alkynyl)toluenesulfonamides; FeCl3; Substituted quinolines; FRIEDLANDER SYNTHESIS; MOLECULAR-IODINE; C BOND; EFFICIENT; ANNULATION; MECHANISM; ARYLATION; ALDEHYDES; KETONES; AMINES;

D O I：

10.1016/j.tetlet.2012.07.047

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of substituted quinolines have been synthesized in moderate to good yields (55-81%) from easily available substrates N-aryl-N-(2-alkynyl)toluenesulfonamides via FeCl3-mediated intramolecular cyclization and concomitant detosylation. (C) 2012 Elsevier Ltd. All rights reserved.

引用

页码：5119 / 5122

页数：4

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