A Comparative Study between Different Phases of Menstrual Cycle Regarding Hemodynamic Response to Laryngeal Mask Airway and Intraocular Pressure Changes in Elective Ophthalmic Surgery

Objective: The aim of the study was to determine the effect of the different phases of the menstrual cycle on hemodynamic response to laryngeal mask airway and intraocular pressure changes in elective ophthalmic surgeries. Methods: 80 ASA I & II female patients were equally allocated in one of two groups: group 1 (follicular) and group 2 (luteal) according to the phases of the menstrual cycle. Patients received propofol and rocuronium and LMA was introduced. Hemodynamic variables and intraocular pressure were recorded before administration of I. V anesthetic and after LMA introduction. Rate pressure products were calculated as well as IOP measurements. Results: Rate pressure products values were significantly increased at the first minute after LMA introduction in group 2 (luteal) compared to group 1 (follicular) (P < 0.001). There was no significant statistical difference between the two groups regarding the intraocular pressure measurements. Conclusion: The phase of the menstrual cycle affects the hemodynamic response to LMA introduction being higher in the luteal phase than in the follicular phase, whereas the different phases have no significant effect on IOP measurements. [Mona Raafat Fahim, Ashraf Darwish, Rehab Sami, Hala Bahy and Rashad Aref. A Comparative Study between Different Phases of Menstrual Cycle Regarding Hemodynamic Response to Laryngeal Mask Airway and Intraocular Pressure Changes in Elective Ophthalmic Surgery. Life Sci J 2012; 9(2): 794-797] (ISSN: 10978135). http://www.lifesciencesite.com. 118