Synthetic ion channel based on metal-organic polyhedra

被引：195
作者：
Jung, Minseon [1 ,2 ]
Kim, Hyunuk [1 ,2 ]
Baek, Kangkyun [1 ,2 ]
Kim, Kimoon [1 ,2 ]
机构：
[1] Pohang Univ Sci & Technol, Natl Creat Res Initiat Ctr Smart Supramol, Pohang 790784, South Korea
[2] Pohang Univ Sci & Technol, Dept Chem, Pohang 790784, South Korea
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2008年 / 47卷 / 31期
关键词：
pi interactions; ion channels; nanostructures; self-assembly; supramolecular chemistry;
D O I：
10.1002/anie.200802240
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
(Figure Presented) MOPping up ions: A synthetic ion channel formed with MOP-18 transports protons and alkali-metal ions across lipid membranes. Homogeneous, long-lived singlechannel currents were observed in planar lipid bilayer experiments. The MOP-18 channel prefers cations over anions, and the cation selectivity is in the order Li+≫Na+K +>Rb+>Cs+. This system is promising for applications such as sensors and catalysis. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码：5755 / 5757
页数：3
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  • [21] Stochastic sensing of organic analytes by a pore-forming protein containing a molecular adapter
    Gu, LQ
    Braha, O
    Conlan, S
    Cheley, S
    Bayley, H
    [J]. NATURE, 1999, 398 (6729) : 686 - 690
  • [22] Hille B., 2001, IONIC CHANNELS EXCIT
  • [23] Sequence-specific detection of individual DNA strands using engineered nanopores
    Howorka, S
    Cheley, S
    Bayley, H
    [J]. NATURE BIOTECHNOLOGY, 2001, 19 (07) : 636 - 639
  • [24] Molecular umbrella-assisted transport of an oligonucleotide across cholesterol-rich phospholipid bilayers
    Janout, V
    Jing, BW
    Regen, SL
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (45) : 15862 - 15870
  • [25] Artificial ion channel formed by cucurbit[n]uril derivatives with a carbonyl group fringed portal reminiscent of the selectivity filter of K+ channels
    Jeon, YJ
    Kim, H
    Jon, S
    Selvapalam, N
    Oh, DH
    Seo, I
    Park, CS
    Jung, SR
    Koh, DS
    Kim, K
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2004, 126 (49) : 15944 - 15945
  • [26] PYRANINE AS A SENSITIVE PH PROBE FOR LIPOSOME INTERIORS AND SURFACES - PH GRADIENTS ACROSS PHOSPHOLIPID VESICLES
    KANO, K
    FENDLER, JH
    [J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1978, 509 (02) : 289 - 299
  • [27] A unimolecular G-quadruplex that functions as a synthetic transmembrane Na+ transporter
    Kaucher, MS
    Harrell, WA
    Davis, JT
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (01) : 38 - 39
  • [28] ARTIFICIAL NONPEPTIDE SINGLE ION CHANNELS
    KOBUKE, Y
    UEDA, K
    SOKABE, M
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1992, 114 (20) : 7618 - 7622
  • [29] Synthetic ion channel activity documented by electrophysiological methods in living cells
    Leevy, WM
    Huettner, JE
    Pajewski, R
    Schlesinger, PH
    Gokel, GW
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2004, 126 (48) : 15747 - 15753
  • [30] Synthetic pores with reactive signal amplifiers as artificial tongues
    Litvinchuk, Svetlana
    Tanaka, Hiroyuki
    Miyatake, Tomohiro
    Pasini, Dario
    Tanaka, Takatsugu
    Bollot, Guillaume
    Mareda, Jiri
    Matile, Stefan
    [J]. NATURE MATERIALS, 2007, 6 (08) : 576 - 580
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