Discovery of Acupoints and Combinations with Potential to Treat Vascular Dementia: A Data Mining Analysis

被引：16

作者：

Feng, Shuwei ^{[1
]}

Ren, Yulan ^{[1
]}

Fan, Shilin ^{[2
]}

Wang, Minyu ^{[1
]}

Sun, Tianxiao ^{[1
]}

Zeng, Fang ^{[1
]}

Li, Ping ^{[2
]}

Liang, Fanrong ^{[1
]}

机构：

[1] Chengdu Univ Tradit Chinese Med, Chengdu 610075, Sichuan, Peoples R China

[2] Southwest Petr Univ, Chengdu 610500, Sichuan, Peoples R China

来源：

EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE | 2015年 / 2015卷

基金：

美国国家科学基金会;

关键词：

ACUPUNCTURE STIMULATION; NEUROTROPHIC FACTOR; ELECTROACUPUNCTURE; EXPRESSION; BAIHUI; BRAIN; IMPAIRMENT; PREVALENCE; CENTRALITY; DOPAMINE;

D O I：

10.1155/2015/310591

中图分类号：

R [医药、卫生];

学科分类号：

10 ;

摘要：

The prevalence of vascular dementia (VaD) is high among the elderly. Acupuncture, a popular therapeutic method in China, can improve memory, orientation, calculation, and self-managing ability in VaD patients. However, in clinical acupuncture and acupuncture research, the selection of acupoints to treat VaD remains challenging. This study aimed to discover acupoints and acupoint combinations with potential for VaD based on data mining. After database searching and screening for articles on clinical trials evaluating the effects of acupuncture on VaD, 238 acupuncture prescriptions were included for further analysis. Baihui (GV 20), Sishencong (EX-HN 1), Fengchi (GB 20), Shuigou (GV 26), and Shenting (GV 24) appeared most frequently in the modern literature and are potential acupoints for VaD. Combinations between Baihui (GV 20), Sishencong (EX-HN 1), Fengchi (GB 20), Shenting (GV 24), Shuigou (GV 26), and Zusanli (ST 36) were most frequent and represent potential combinations for VaD treatment. These results provide a reference for the selection and combination of acupoints to treat VaD in clinical acupuncture and acupuncture research.

引用

页数：12

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