Programming of Osteoporosis and Impact on Osteoporosis Risk

被引:22
作者
Dennison, Elaine M. [1 ]
Harvey, Nicholas C. [1 ]
Cooper, Cyrus [1 ,2 ]
机构
[1] Univ Southampton, Southampton Gen Hosp, MRC, Lifecourse Epidemiol Unit, Southampton SO16 6YD, Hants, England
[2] Univ Oxford, NIHR Musculoskeletal Biomed Res Unit, Oxford, England
基金
英国医学研究理事会; 英国惠康基金;
关键词
osteoporosis; programming; bone; fracture; nutrition; cohort; ADULT BONE MASS; BIRTH-WEIGHT; LATER LIFE; HERTFORDSHIRE COHORT; CHILDHOOD GROWTH; HIP FRACTURE; PREGNANCY; INFANCY; GENE;
D O I
10.1097/GRF.0b013e31829cb9b0
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Osteoporosis is a skeletal disorder characterized by reduced bone quantity and quality and an increased susceptibility to fracture, and seems to be one of many chronic conditions that might be influenced by events early in life. Specifically, there is growing evidence of an interaction between the genome and the environment in the expression of the disease.
引用
收藏
页码:549 / 555
页数:7
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