Glutathione and related enzymes:: Biological roles and importance in pathological processes

被引：84
作者：
Huber, Paula C. [1 ,2 ]
Almeida, Wanda P. [1 ,2 ]
de Fatima, Angelo [3 ]
机构：
[1] Univ Estadual Campinas, Curso Farm, BR-13084971 Campinas, SP, Brazil
[2] Univ Estadual Campinas, Dept Quim Organ, Inst Quim, BR-13084971 Campinas, SP, Brazil
[3] Univ Fed Minas Gerais, Dept Quim, Inst Ciencias Exatas, BR-31270901 Belo Horizonte, MG, Brazil
来源：
QUIMICA NOVA | 2008年 / 31卷 / 05期
关键词：
glutathione; oxidative stress; cancer;
D O I：
10.1590/S0100-40422008000500046
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Glutathione (GSH) and related enzymes are pivoted for the normal functioning of several important biological processes. In this review we discuss the biosynthesis and the catalytic cycles of glutathione as well as the major GSH-related enzymes. We also present how glutathione and enzymes are involved in cancer and the chromatographic and non-chromatographic methods used to analyze glutathione and/or its derivatives.
引用
收藏
页码：1170 / 1179
页数：10
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