MCScanX-transposed: detecting transposed gene duplications based on multiple colinearity scans

被引：152

作者：

Wang, Yupeng ^{[1
,2
]}

Li, Jingping ^{[1
]}

Paterson, Andrew H. ^{[1
]}

机构：

[1] Univ Georgia, Plant Genome Mapping Lab, Athens, GA 30602 USA

[2] Cornell Univ, Computat Biol Serv Unit, Ithaca, NY 14853 USA

来源：

BIOINFORMATICS | 2013年 / 29卷 / 11期

基金：

美国国家科学基金会;

关键词：

GENOME; ARABIDOPSIS; EXPRESSION;

D O I：

10.1093/bioinformatics/btt150

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Gene duplication occurs via different modes such as segmental and single-gene duplications. Transposed gene duplication, a specific form of single-gene duplication, 'copies' a gene from an ancestral chromosomal location to a novel location. MCScanX is a toolkit for detection and evolutionary analysis of gene colinearity. We have developed MCScanX-transposed, a software package to detect transposed gene duplications that occurred within different epochs, based on execution of MCScanX within and between related genomes. MCScanX-transposed can be also used for integrative analysis of gene duplication modes for a genome and to annotate a gene family of interest with gene duplication modes.

引用

页码：1458 / 1460

页数：3

共 15 条

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