MCScanX-transposed: detecting transposed gene duplications based on multiple colinearity scans

被引:152
作者
Wang, Yupeng [1 ,2 ]
Li, Jingping [1 ]
Paterson, Andrew H. [1 ]
机构
[1] Univ Georgia, Plant Genome Mapping Lab, Athens, GA 30602 USA
[2] Cornell Univ, Computat Biol Serv Unit, Ithaca, NY 14853 USA
基金
美国国家科学基金会;
关键词
GENOME; ARABIDOPSIS; EXPRESSION;
D O I
10.1093/bioinformatics/btt150
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Gene duplication occurs via different modes such as segmental and single-gene duplications. Transposed gene duplication, a specific form of single-gene duplication, 'copies' a gene from an ancestral chromosomal location to a novel location. MCScanX is a toolkit for detection and evolutionary analysis of gene colinearity. We have developed MCScanX-transposed, a software package to detect transposed gene duplications that occurred within different epochs, based on execution of MCScanX within and between related genomes. MCScanX-transposed can be also used for integrative analysis of gene duplication modes for a genome and to annotate a gene family of interest with gene duplication modes.
引用
收藏
页码:1458 / 1460
页数:3
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