Regioselective Palladium(0)-Catalyzed Cross-Coupling Reactions of 5,7-Dichloro-1,6-naphthyridine

被引：9

作者：

Ali, Iftikhar ^{[1
]}

Hassan, Zahid ^{[1
]}

Hein, Martin ^{[1
]}

Falodun, Abiodun ^{[1
,2
]}

Patonay, Tamas ^{[3
]}

Villinger, Alexander ^{[1
]}

Langer, Peter ^{[1
,4
]}

机构：

[1] Univ Rostock, Inst Chem, D-18059 Rostock, Germany

[2] Univ Benin, Dept Pharmaceut Chem, Fac Pharm, Benin 30001, Nigeria

[3] Univ Debrecen, Dept Organ Chem, H-4032 Debrecen, Hungary

[4] Univ Rostock, Leibniz Inst Katalyse, D-18059 Rostock, Germany

来源：

SYNTHESIS-STUTTGART | 2012年 / 44卷 / 14期

关键词：

catalysis; palladium; Suzuki reaction; naphthyridine; regioselectivity; 1,8-NAPHTHYRIDINE DERIVATIVES; BOND FORMATION; INHIBITORS; DISCOVERY; PROFILE; POTENT; ACETYLCHOLINESTERASE/BUTYRYLCHOLINESTERASE; HETEROCYCLES; ANTAGONISTS; RECEPTORS;

D O I：

10.1055/s-0032-1316540

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A variety of mono- and diarylated naphthyridine derivatives were prepared by site-selective Suzuki-Miyaura cross-coupling reactions of 5,7-dichloro-1,6-naphthyridine. The first attack occurs at position 5.

引用

收藏

页码：2255 / 2263

页数：9

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