Simultaneous imaging of lysosomal and mitochondrial viscosity during mitophagy using molecular rotors with dual-color emission

被引：22
|
作者：
Chen, Wen [1 ]
Han, Junyan [1 ]
She, Jiaxin [1 ]
Wang, Fenglin [1 ]
Zhu, Lei [1 ]
Yu, Ru-Qin [1 ]
Jiang, Jian-Hui [1 ]
机构：
[1] Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2020年 / 56卷 / 56期
基金：
中国国家自然科学基金;
关键词：
FLUORESCENT-PROBE;
D O I：
10.1039/d0cc00868k
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Two molecular rotors with a single excitation and dual-color emission wavelengths were engineered for simultaneous imaging of lysosomal and mitochondrial viscosity. These two molecular rotors were highly sensitive to viscosity without dependence on pH or polarity, facilitating simultaneous imaging of lysosomal and mitochondrial viscosity during mitophagy in living cells.
引用
收藏
页码：7797 / 7800
页数：4
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