Clinical Characteristics, Management, and Factors Associated with Poor Visual Prognosis of Acute Retinal Necrosis

被引：14

作者：

Takase, Hiroshi ^{[1
]}

Goto, Hiroshi ^{[2
]}

Namba, Kenichi ^{[3
,4
]}

Mizuki, Nobuhisa ^{[5
]}

Okada, Annabelle A. ^{[6
]}

Ohguro, Nobuyuki ^{[7
]}

Sonoda, Koh-Hei ^{[8
]}

Tomita, Makoto ^{[9
]}

Keino, Hiroshi ^{[6
]}

Kezuka, Takeshi ^{[2
]}

Kubono, Reo ^{[1
]}

Mizuuchi, Kazuomi ^{[3
,4
]}

Shibuya, Etsuko ^{[5
]}

Takahashi, Hiroyuki ^{[1
]}

Yanai, Ryoji ^{[10
]}

Mochizuki, Manabu ^{[1
,11
]}

机构：

[1] Tokyo Med & Dent Univ, Grad Sch Med & Dent Sci, Dept Ophthalmol & Visual Sci, Tokyo 1138519, Japan

[2] Tokyo Med Univ, Dept Ophthalmol, Tokyo, Japan

[3] Hokkaido Univ, Dept Ophthalmol, Fac Med, Sapporo, Hokkaido, Japan

[4] Hokkaido Univ, Grad Sch Med, Sapporo, Hokkaido, Japan

[5] Yokohama City Univ, Dept Ophthalmol & Visual Sci, Grad Sch Med, Yokohama, Kanagawa, Japan

[6] Kyorin Univ, Dept Ophthalmol, Sch Med, Tokyo, Japan

[7] Osaka Hosp, Dept Ophthalmol, Japan Community Hlth Care Org, Osaka, Japan

[8] Kyushu Univ, Dept Ophthalmol, Grad Sch Med, Fukuoka, Japan

[9] Yokohama City Univ, Sch Data Sci, Yokohama, Kanagawa, Japan

[10] Yamaguchi Univ, Dept Ophthalmol, Grad Sch Med, Yamaguchi, Japan

[11] Miyata Eye Hosp, Dept Ophthalmol, Miyazaki, Japan

来源：

OCULAR IMMUNOLOGY AND INFLAMMATION | 2022年 / 30卷 / 01期

关键词：

Acute retinal necrosis; uveitis; nationwide survey; prognostic factor; ocular characteristics; EPIDEMIOLOGIC SURVEY; DIAGNOSTIC-CRITERIA;

D O I：

10.1080/09273948.2020.1789179

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Purpose: To identify the clinical characteristics of acute retinal necrosis (ARN) and clarify factors associated with poor visual prognosis. Methods: a nationwide multi-center retrospective chart review study was performed in Japan using data from the medical records of 149 consecutive ARN patients. Demographics, ocular signs, virologic testing of intraocular fluids, and treatment were examined. Factors associated with poor visual prognosis were investigated by regression analysis. Results: At initial presentation, anterior chamber cells or mutton-fat keratic precipitates (97%), unilaterality (93%), and yellow-white retinal lesions (86%) were recognized. In the clinical course, rapid circumferential expansion of retinal lesions (39%), development of retinal break or retinal detachment (55%), and optic atrophy (43%) were recorded. Four variables were identified as associated with poor visual prognosis. Conclusions: The present study identified clinical characteristics and factors associated with poor visual prognosis of ARN.

引用

页码：48 / 53

页数：6

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