MULTIPLE SCLEROSIS Oral laquinimod for MS-bringing the brain into focus

被引：8

作者：

Brueck, Wolfgang ^{[1
]}

Vollmer, Timothy ^{[2
]}

机构：

[1] Univ Gottingen, Univ Med Ctr Gottingen, Inst Neuropathol, D-37075 Gottingen, Germany

[2] Univ Colorado, Dept Neurol, Aurora, CO 80045 USA

来源：

NATURE REVIEWS NEUROLOGY | 2013年 / 9卷 / 12期

关键词：

D O I：

10.1038/nrneurol.2013.234

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Currently approved multiple sclerosis (MS) treatments mainly target the peripheral immune system, thereby reducing relapse rates and MRI markers of inflammation. A recent phase III trial indicates that laquinimod, a new orally active immunomodulator, has a CNS-intrinsic mode of action that is independent of effects on the peripheral immune response.

引用

页码：664 / 665

页数：3

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