Optimal blockade of the renin-angiotensin-aldosterone system

被引：13
|
作者：
Nussberger, Juerg [1 ]
Bohlender, Juergen [2 ]
机构：
[1] CHU Vaudois, Dept Internal Med, Div Angiol & Hypertens, CH-1011 Lausanne, Switzerland
[2] Hop Fribourgeois, Med Clin, CH-1708 Fribourg, Switzerland
来源：
NATURE REVIEWS CARDIOLOGY | 2013年 / 10卷 / 04期
关键词：
ALISKIREN; INHIBITION;
D O I：
10.1038/nrcardio.2013.28
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Inhibition of the renin-angiotensin-aldosterone system (RAAS) is a successful therapy for hypertension, heart failure, and renal insufficiency. Overdosing of RAAS inhibitors is occasionally observed when several agents are used together, and can cause adverse events such as hypotension, hyperkalaemia, and renal failure. We advocate optimal, rather than complete, RAAS blockade. Nussberger, J. & Bohlender, J. Nat. Rev. Cardiol. 10, 183-184 (2013); published online 12 March 2013; doi:10.1038/nrcardio.2013.28
引用
收藏
页码：183 / 184
页数：2
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