Iterative Synthesis of 1,3,5-Polyphenylene Dendrons via C-H Activation

被引：36

作者：

Finke, Aaron D. ^{[1
]}

Moore, Jeffrey S. ^{[1
]}

机构：

[1] Univ Illinois, Dept Chem, Urbana, IL 61801 USA

来源：

ORGANIC LETTERS | 2008年 / 10卷 / 21期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1021/ol8019605

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An iterative synthesis of 1,3,5-polyphenylene dendrons via C-H activation/Suzuki-Miyaura coupling up to a third generation dendron is described. C-H bonds at the focal points of the dendrons are selectively borylated via iridium-catalyzed borylation, eliminating the need for reactive protecting groups, Sequential additions of low catalyst loadings efficiently borylate higher-generation dendrons, whereas higher initial catalyst loadings are less efficient.

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页码：4851 / 4854

页数：4

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