The effect of Ge and oxygen content on microstructural formation and mechanical properties of Ti-Nb alloys were investigated in order to design a desirable Ti based alloy through casting process. Three phase mixtures consisting of bcc-structured beta phase, orthorhombic structured alpha '' phase and intermediate omega phase were found depending on Nb, Ge, oxygen content in the present alloy system. The volume fraction of alpha '' phase and omega phase decreased with increasing Ge or oxygen content. This microstructural information may indicate that both Ge and oxygen act to increase the stability of beta phase rather than alpha '' phase in metastable beta-Ti based alloys prepared by water quenching. Elastic modulus values were sensitive to phase stability of constituent phases.