Efficacy of eculizumab in refractory life-threatening warm autoimmune hemolytic anemia associated with chronic myelomonocytic leukemia

被引:7
作者
Gauchy, Anne-Cecile [1 ,2 ]
Hentzien, Maxime [2 ,3 ]
Wynckel, Alain [4 ]
de Marcellus, Victoire [1 ,2 ]
Rodier, Cyrielle [1 ,2 ]
Delmer, Alain [1 ,2 ]
Quinquenel, Anne [1 ,2 ]
机构
[1] Ctr Hosp Univ, Hop Robert Debre, Serv Hematol Clin, Reims, France
[2] Univ Reims, UFR Med, Reims, France
[3] Ctr Hosp Univ, Hop Robert Debre, Serv Med Interne Malad Infect & Immunol Clin, Reims, France
[4] Ctr Hosp Univ, Hop Robert Debre, Serv Nephrol, Reims, France
来源
CLINICAL CASE REPORTS | 2020年 / 8卷 / 12期
关键词
chronic myelomonocytic leukemia; eculizumab; warm autoimmune hemolytic anemia; MYELODYSPLASTIC SYNDROMES; AZACITIDINE; DISORDERS; RITUXIMAB; DISEASES;
D O I
10.1002/ccr3.3250
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Eculizumab may be considered as an emergency therapeutic option in refractory life-threatening warm autoimmune hemolytic anemia especially if direct antiglobulin test is positive for both IgG and C3d and after failure of all conventional treatments.
引用
收藏
页码:2641 / 2644
页数:4
相关论文
共 13 条
  • [1] Infections associated with the use of eculizumab: recommendations for prevention and prophylaxis
    Benamu, Esther
    Montoya, Jose G.
    [J]. CURRENT OPINION IN INFECTIOUS DISEASES, 2016, 29 (04) : 319 - 329
  • [2] Efficacy of Azacitidine in autoimmune and inflammatory disorders associated with myelodysplastic syndromes and chronic myelomonocytic leukemia
    Fraison, Jean-Baptiste
    Mekinian, Arsene
    Grignano, Eric
    Kahn, Jean-Emmanuel
    Arlet, Jean-Benoit
    Decaux, Olivier
    Denis, Guillaume
    Buchdahl, Anne-Laure
    Omouri, Mohamed
    Maigne, Gwenola
    Aouba, Achille
    Leon, Nathalie
    Berthier, Sabine
    Liozon, Eric
    Park, Sophie
    Gardin, Claude
    Lortholary, Olivier
    Rossignol, Julien
    Fenaux, Pierre
    Fain, Olivier
    Braun, Thorsten
    [J]. LEUKEMIA RESEARCH, 2016, 43 : 13 - 17
  • [3] Autoimmune and inflammatory diseases associated with chronic myelomonocytic leukemia: A series of 26 cases and literature review
    Grignano, Eric
    Mekinian, Arsene
    Braun, Thorsten
    Liozon, Eric
    Hamidou, Mohamed
    Decaux, Olivier
    Puechal, Xavier
    Kahn, Jean Emmanuel
    Schoindre, Yoland
    Rossignol, Julien
    Lortholary, Olivier
    Lioger, Bertrand
    Hermine, Olivier
    Park, Sophie
    Ades, Lionel
    Montestruc, Francois
    Ricard, Laure
    Gardin, Claude
    Fenaux, Pierre
    Fain, Olivier
    [J]. LEUKEMIA RESEARCH, 2016, 47 : 136 - 141
  • [4] Immune thrombocytopenia in chronic myelomonocytic leukemia
    Hadjadj, Jerome
    Michel, Marc
    Chauveheid, Marie-Paule
    Godeau, Bertrand
    Papo, Thomas
    Sacre, Karim
    [J]. EUROPEAN JOURNAL OF HAEMATOLOGY, 2014, 93 (06) : 521 - 526
  • [5] Refractory IgG Warm Autoimmune Hemolytic Anemia Treated with Eculizumab: A Novel Application of Anticomplement Therapy
    Ma, Kim
    Caplan, Stephen
    [J]. CASE REPORTS IN HEMATOLOGY, 2016, 2016
  • [6] Complement deposition in autoimmune hemolytic anemia is a footprint for difficult-to-detect IgM autoantibodies
    Meulenbroek, Elisabeth M.
    de Haas, Masja
    Brouwer, Conny
    Folman, Claudia
    Zeerleder, Sacha S.
    Wouters, Diana
    [J]. HAEMATOLOGICA, 2015, 100 (11) : 1407 - 1414
  • [7] A Close Association of Autoimmune-Mediated Processes and Autoimmune Disorders with Chronic Myelomonocytic Leukemia: Observation from a Single Institution
    Peker, Deniz
    Padron, Eric
    Bennett, John M.
    Zhang, Xiaohui
    Horna, Pedro
    Epling-Burnette, Pearlie K.
    Lancet, Jeffrey E.
    Pinilla-Ibarz, Javier
    Moscinski, Lynn
    List, Alan F.
    Komrokji, Rami S.
    Zhang, Ling
    [J]. ACTA HAEMATOLOGICA, 2015, 133 (02) : 249 - 256
  • [8] Efficacy and safety of rituximab in auto-immune hemolytic anemia: A meta-analysis of 21 studies
    Reynaud, Quitterie
    Durieu, Isabelle
    Dutertre, Marine
    Ledochowski, Stanislas
    Durupt, Stephane
    Michallet, Anne-Sophie
    Vital-Durand, Denis
    Lega, Jean-Christophe
    [J]. AUTOIMMUNITY REVIEWS, 2015, 14 (04) : 304 - 313
  • [9] Eculizumab in cold agglutinin disease (DECADE): an open-label, prospective, bicentric, nonrandomized phase 2 trial
    Roeth, Alexander
    Bommer, Martin
    Huettmann, Andreas
    Herich-Terhuerne, Doerte
    Kuklik, Nils
    Rekowski, Jan
    Lenz, Veronika
    Schrezenmeier, Hubert
    Duehrsen, Ulrich
    [J]. BLOOD ADVANCES, 2018, 2 (19) : 2543 - 2549
  • [10] Azacitidine: A Review in Myelodysplastic Syndromes and Acute Myeloid Leukaemia
    Scott, Lesley J.
    [J]. DRUGS, 2016, 76 (08) : 889 - 900