Gastric Pepsin in Middle Ear Fluid of Children With Otitis Media: Clinical Implications

被引：18

作者：

He, Zhaoping ^{[1
]}

O'Reilly, Robert C. ^{[1
]}

Mehta, Devendra ^{[1
]}

机构：

[1] Alfred I DuPont Hosp Children, Div Pediat Otolaryngol, Wilmington, DE 19899 USA

来源：

CURRENT ALLERGY AND ASTHMA REPORTS | 2008年 / 8卷 / 06期

关键词：

D O I：

10.1007/s11882-008-0094-7

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Gastroesophageal reflux and extraesophageal reflux have been postulated to be involved in the pathogenesis of otitis media. This is supported by recent studies revealing the presence of gastric pepsin in the middle ear space of children with otitis media but not in control patients without otitis media. Reflux's role in otitis media appears to be most pronounced in younger children and those with purulent effusions.

引用

页码：513 / 518

页数：6

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