Current concepts in pediatric liver tumors

被引：46

作者：

Emre, Sukru ^{[1
,2
]}

Umman, Veysel ^{[1
,2
]}

Rodriguez-Davalos, Manuel ^{[1
,2
]}

机构：

[1] Yale Univ, Sch Med, Sect Transplantat & Immunol, Dept Surg, New Haven, CT 06520 USA

[2] Yale New Haven Transplantat Ctr, New Haven, CT USA

来源：

PEDIATRIC TRANSPLANTATION | 2012年 / 16卷 / 06期

关键词：

pediatric liver transplantation; hepatoblastoma; malignancy; literature review; FOCAL NODULAR HYPERPLASIA; UNDIFFERENTIATED EMBRYONAL SARCOMA; SIROLIMUS-BASED IMMUNOSUPPRESSION; OF-THE-LITERATURE; DISEASE TYPE-I; UNRESECTABLE HEPATOCELLULAR-CARCINOMA; FAMILIAL ADENOMATOUS POLYPOSIS; HIGH-DOSE METHYLPREDNISOLONE; STROMAL EPITHELIAL TUMOR; INTERNATIONAL-SOCIETY;

D O I：

10.1111/j.1399-3046.2012.01704.x

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Emre S, Umman V, Rodriguez-Davalos M. Current concepts in pediatric liver tumors. Abstract: Liver tumors in children can be classified into benign or malignant; some of the benign lesions can have the potential of malignant transformation, and therefore the therapeutic approach may change. These neoplasms account for nearly 12% of all pediatric tumors and they have gained significant attention in the last decades due to data suggesting that the incidence may be increasing 5% annually. We know that with new and improved imaging modalities some of these lesions may be detected more often than before. Recent studies showed that liver cancer represented 2% of malignancies in infants by 1980s and this was doubled in incidence to 4% in the following 10 yr. In this review our aim is to discuss all primary liver tumors in children with attention to their clinicopathological and immunohistochemical features followed by the current standard of care.

引用

页码：549 / 563

页数：15