Pitfalls in Challenging Thyroid Tumors: Emphasis on Differential Diagnosis and Ancillary Biomarkers

被引:24
作者
Cameselle-Teijeiro, Jose Manuel [1 ,2 ,3 ]
Eloy, Catarina [4 ,5 ,6 ]
Sobrinho-Simoes, Manuel [4 ,5 ,6 ,7 ]
机构
[1] Hlth Res Inst Santiago de Compostela IDIS, Clin Univ Hosp, Dept Pathol, Galician Healthcare Serv SERGAS, Santiago De Compostela, Spain
[2] Univ Santiago de Compostela, Med Fac, Santiago De Compostela, Spain
[3] Clin Univ Hosp, Dept Anat Pathol, Travesia Choupana S-N, Santiago De Compostela 15706, Spain
[4] I3S Inst Invest & Inovacao Saude, Porto, Portugal
[5] Univ Porto, Inst Mol Pathol & Immunol, Porto, Portugal
[6] Univ Porto, Med Fac, Porto, Portugal
[7] Ctr Hosp S Joao, Dept Pathol, Porto, Portugal
关键词
Thyroid; Rare tumors; PTC variants; FTC variants; Differential diagnosis; Molecular pathology; SCLEROSING MUCOEPIDERMOID CARCINOMA; SQUAMOUS-CELL CARCINOMA; THYMUS-LIKE DIFFERENTIATION; CRIBRIFORM-MORULAR VARIANT; PROMINENT HOBNAIL FEATURES; ANALOG SECRETORY CARCINOMA; FASCIITIS-LIKE STROMA; FOLLICULAR CARCINOMA; MIXED MEDULLARY; PAPILLARY CARCINOMA;
D O I
10.1007/s12022-020-09638-x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Thyroid pathology encompasses a heterogenous group of clinicopathological entities including rare and diagnostically challenging neoplasms. The review is focused on morphological, immunohistochemical, and molecular features of rare thyroid neoplasms that can pose diagnostic problems. The tumors are organized based on growth patterns including thyroid neoplasms with predominantly papillary, follicular, solid, and spindle cell growth pattern, as well as neoplasms with distinct cytological characteristics. A special section is also dedicated to rare thyroid tumors with peculiar patterns including thyroid carcinoma with Ewing family tumor elements and intrathyroidal thymic-related neoplasms.
引用
收藏
页码:197 / 217
页数:21
相关论文
共 152 条
[1]   Molecular Characterization of an Endometrial Endometrioid Adenocarcinoma Metastatic to a Thyroid Hurthle Cell Adenoma Showing Cancerization of Follicles [J].
Afrogheh, Amir H. ;
Meserve, Emily ;
Sadow, Peter M. ;
Stephen, Antonia E. ;
Nose, Vania ;
Berlin, Suzanne ;
Faquin, William C. .
ENDOCRINE PATHOLOGY, 2016, 27 (03) :213-219
[2]   Malignant teratoid tumor of the thyroid gland: an aggressive primitive multiphenotypic malignancy showing organotypical elements and frequent DICER1 alterations-is the term "thyroblastoma" more appropriate? [J].
Agaimy, Abbas ;
Witkowski, Leora ;
Stoehr, Robert ;
Castillo Cuenca, Joseph Christopher ;
Alberto Gonzalez-Muller, Carlos ;
Bruetting, Alfred ;
Baehrle, Markus ;
Mantsopoulos, Konstantinos ;
Amin, Randa M. S. ;
Hartmann, Arndt ;
Metzler, Markus ;
Amr, Samir S. ;
Foulkes, William D. ;
Sobrinho-Simoes, Manuel ;
Eloy, Catarina .
VIRCHOWS ARCHIV, 2020, 477 (06) :787-798
[3]   Hobnail cells in encapsulated papillary thyroid carcinoma: Report of 2 cases with immunohistochemical and molecular findings and literature analysis [J].
Agarwal, Shweta ;
Sadiq, Qandeel ;
Ortanca, Ibrahim .
PATHOLOGY RESEARCH AND PRACTICE, 2020, 216 (03)
[4]   Colon Cancer Metastasis Within a NIFTP: A Case Report and Review of the Literature [J].
Al Battal, Miriam ;
Kanaan, Christina ;
Labaied, Nizar ;
Breuskin, Ingrid ;
Leboulleux, Sophie ;
Soufan, Ranya ;
Scoazec, Jean-Yves ;
Al Ghuzlan, Abir .
HEAD & NECK PATHOLOGY, 2020, 14 (03) :833-836
[5]   Discrepant serum and urine β-hCG results due to production of β-hCG by a cribriform-morular variant of thyroid papillary carcinoma [J].
Alikhan, Mir ;
Koshy, Anoopa ;
Hyjek, Elizabeth ;
Stenson, Kerstin ;
Cohen, Ronald N. ;
Yeo, Kiang-Teck J. .
CLINICA CHIMICA ACTA, 2015, 438 :181-185
[6]  
Amacher AM, 2015, AM J SURG PATHOL, V39, P260, DOI 10.1097/PAS.0000000000000329
[7]   Hobnail Variant of Papillary Thyroid Carcinoma: a Literature Review [J].
Ambrosi, Francesca ;
Righi, Alberto ;
Ricci, Costantino ;
Erickson, Lori A. ;
Lloyd, Ricardo V. ;
Asioli, Sofia .
ENDOCRINE PATHOLOGY, 2017, 28 (04) :293-301
[8]   Neoplastic metastases to the endocrine glands [J].
Angelousi, Anna ;
Alexandraki, Krystallenia, I ;
Kyriakopoulos, George ;
Tsoli, Marina ;
Thomas, Dimitrios ;
Kaltsas, Gregory ;
Grossman, Ashley .
ENDOCRINE-RELATED CANCER, 2020, 27 (01) :R1-R20
[9]   PRIMARY THYROID THYMOMA - A DISTINCT CLINICOPATHOLOGIC ENTITY [J].
ASA, SL ;
DARDICK, I ;
VANNOSTRAND, AWP ;
BAILEY, DJ ;
GULLANE, PJ .
HUMAN PATHOLOGY, 1988, 19 (12) :1463-1466
[10]   An Unusual Salivary Gland Tumor Mimicking Papillary Thyroid Carcinoma: Mammary Analog Secretory Carcinoma [J].
Asa, Sylvia L. ;
Mete, Ozgur .
FRONTIERS IN ENDOCRINOLOGY, 2018, 9