Chemical study and larvicidal activity against Aedes aegypti of essential oil of Piper aduncum L. (Piperaceae)

被引：39

作者：

Oliveira, Gisele L. ^{[1
]}

Cardoso, Sheila K. ^{[2
]}

Lara Junior, Celio R. ^{[2
]}

Vieira, Thallyta M. ^{[3
]}

Guimaraes, Elsie F. ^{[4
]}

Figueiredo, Lourdes S. ^{[5
]}

Martins, Ernane R. ^{[5
]}

Moreira, Davyson L. ^{[6
]}

Kaplan, Maria Auxiliadora C. ^{[7
]}

机构：

[1] Univ Fed Rio de Janeiro, Ctr Ciencias Saude, Programa Posgrad Biotecnol Vegetal, UFRJ, BR-21941590 Rio De Janeiro, RJ, Brazil

[2] Fac Saude Ibituruna FASI, BR-39401303 Montes Claros, MG, Brazil

[3] Univ Fed Minas Gerais, Programa Posgrad Ciencias Agr, UFMG, BR-39404006 Montes Claros, MG, Brazil

[4] Inst Pesquisa Jardim Bot Rio De Janeiro, Dept Bot, BR-22460030 Rio De Janeiro, RJ, Brazil

[5] Univ Fed Minas Gerais, Inst Ciencias Agr, UFMG, BR-39404006 Montes Claros, MG, Brazil

[6] Fiocruz MS, Fundacao Oswaldo Cruz, Farmanguinhos, Dept Nat Prod, BR-21045900 Rio De Janeiro, RJ, Brazil

[7] Univ Fed Rio de Janeiro, Ctr Ciencias Saude, Nucleo Pesquisa Prod Nat, UFRJ, BR-21941590 Rio De Janeiro, RJ, Brazil

来源：

ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS | 2013年 / 85卷 / 04期

关键词：

Piper aduncum; Aedes aegypti; larvicidal activity; dengue; 1,8-cineole; GC-MS;

D O I：

10.1590/0001-3765201391011

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Piper aduncum L. is used in folk medicine to treat respiratory and inflammatory diseases. The aim of this study was to analyze the essential oil from leaves of P. aduncum collected in the Brazilian Cerrado, North of Minas Gerais, as well as to evaluate the larvicidal activity of this oil and of its major constituent. The essential oil was analyzed by gas chromatography coupled to flame ionization detector and gas chromatography coupled to mass spectrometry that allowed characterizing 23 compounds (monoterpenes: 90.4%; sesquiterpenes: 7.0%). The major component was 1,8-cineole (53.9%). This oil showed to be very different from those obtained from the same species. Larvae of A. aegypti were exposed to different concentrations of the essential oil and 1,8-cineole. The mortality rate of 100% was obtained after 24h of treatment with the oil at concentrations of 500 and 1,000 ppm. After 48h of treatment, the mortality rate was 80% and 50% for concentrations of 250 and 100 ppm, respectively. The LC50 obtained after 24h was estimated in 289.9 ppm and after 48h was 134.1 ppm. The major compound 1,8-cineole showed no larvicidal activity.

引用

页码：1227 / 1234

页数：8

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