Animal models of axon regeneration after spinal cord injury

被引：47

作者：

Lee, Do-Hun ^{[1
]}

Lee, Jae K. ^{[1
]}

机构：

[1] Univ Miami, Sch Med, Miami Project Cure Paralysis, Dept Neurol Surg, Miami, FL 33136 USA

来源：

NEUROSCIENCE BULLETIN | 2013年 / 29卷 / 04期

关键词：

pyramidotomy; strain differences; contusion; injury models; CORTICOSPINAL TRACT; FUNCTIONAL RECOVERY; CONTUSION INJURY; DEFICIENT MICE; GROWTH; MOUSE; RAT; LESION; PLASTICITY; STRAINS;

D O I：

10.1007/s12264-013-1365-4

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

With advances in genetic and imaging techniques, investigating axon regeneration after spinal cord injury in vivo is becoming more common in the literature. However, there are many issues to consider when using animal models of axon regeneration, including species, strains and injury models. No single particular model suits all types of experiments and each hypothesis being tested requires careful selection of the appropriate animal model. in this review, we describe several commonly-used animal models of axon regeneration in the spinal cord and discuss their advantages and disadvantages.

引用

页码：436 / 444

页数：9

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