Novel type of staphylococcal cassette chromosome mec identified in community-acquired methicillin-resistant Staphylococcus aureus strains

被引：436
作者：
Ma, XX
Ito, T
Tiensasitorn, C
Jamklang, M
Chongtrakool, P
Boyle-Vavra, S
Daum, RS
Hiramatsu, K
机构：
[1] Juntendo Univ, Dept Bacteriol, Bunkyo Ku, Tokyo 1138421, Japan
[2] Univ Chicago, Childrens Hosp, Dept Pediat, Chicago, IL 60637 USA
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2002年 / 46卷 / 04期
关键词：
D O I：
10.1128/AAC.46.4.1147-1152.2002
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
We identified a new type of staphylococcal cassette chromosome mec (SCCmec) from two community-acquired methicillin-resistant Staphylococcus aureus (MRSA) strains. The novel element, designated type IV SCCmec, had a unique combination of the class B mec gene complex and the type 2 ccr gene complex and was much smaller in size (21 to 24 kb) than previously identified SCCmec elements of hospital-acquired MRSA. Consistent with the strains' susceptibilities to various non-beta-lactam antibiotics, the type IV SCCmec was devoid of any antibiotic resistance genes other than the mecA gene.
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页码：1147 / 1152
页数：6
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