Purpose: The aim of this paper is to compare the experience of stigma by persons with epilepsy in Sweden and Iran. Method: An adapted version of the Internalized Stigma of Mental Illness Scale was completed by 130 persons with epilepsy in Tehran and 93 patients at a neurology clinic in Sweden. Results: The Swedish subjects reported a significantly lower level of experienced stigmatization than the Iranian patients, which we think is an effect of a more individualized medical treatment and a longer experience of health education in the Swedish society. Conclusion: Improved seizure control, legislative measures and health education are major contributory factors for stigma reduction in a society as regards epilepsy and probably also other medical conditions. (C) 2013 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.