Difluoromethyl 2-pyridyl sulfone: a versatile carbonyl gem-difluoroolefination reagent

被引：88

作者：

Gao, Bing ^{[1
]}

Zhao, Yanchuan ^{[1
]}

Hu, Jingyu ^{[1
]}

Hu, Jinbo ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Organofluorine Chem, Shanghai 200032, Peoples R China

来源：

ORGANIC CHEMISTRY FRONTIERS | 2015年 / 2卷 / 02期

基金：

中国国家自然科学基金;

关键词：

NUCLEOPHILIC TRIFLUOROMETHYLATION; EFFICIENT SYNTHESIS; DERIVATIVES; 1,1-DIFLUORO-1-ALKENES; OLEFINATION; ALDEHYDES; ALKENES; KETONES; FLUOROALKYLATIONS; DIFLUOROALKENES;

D O I：

10.1039/c4qo00291a

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

This tutorial account describes a robust carbonyl gem-difluoroolefination reagent, difluoromethyl 2-pyridyl sulfone (2-PySO2CF2H), developed by our group, recently. The guidelines for its laboratory preparation and application are presented in detail for potential users.

引用

页码：163 / 168

页数：6

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