Studies on the structure-property relationship of sodium alginate based thixotropic hydrogels

被引：16
|
作者：
Chejara, Dharmesh R. [1 ,2 ]
Kondaveeti, Stalin [1 ]
Prasad, Kamalesh [1 ,2 ]
Siddhanta, A. K. [1 ,2 ]
机构：
[1] CSIR, Cent Salt & Marine Chem Res Inst, Marine Biotechnol & Ecol Discipline, GB Marg, Bhavnagar 364002, Gujarat, India
[2] Acad Sci & Innovat Res, New Delhi 110001, India
来源：
RSC ADVANCES | 2013年 / 3卷 / 36期
关键词：
DRUG-DELIVERY; GEL; CONJUGATE; DESIGN;
D O I：
10.1039/c3ra43070g
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Sodium alginate (Na-Alg) reacted with 1-naphthylamine in the presence of 1-ethyl-3-[3-(dimethylamino)propyl]-carbodiimide hydrochloride (EDC center dot HCl) affording an amide derivative capable of forming soft hydrogel at a concentration of 4% w/v. The latter upon gentle stirring turned into a viscous sol, which assumed the original gel structure upon standing at room temperature in a reversible process. Such thixotropic materials have the potential to be used in biomedical applications and as sensors.
引用
收藏
页码：15744 / 15751
页数：8
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