Multicenter surveillance study of surgical site infection and its risk factors in radical resection of colon or rectal carcinoma

被引：32

作者：

Du, Mingmei ^{[1
]}

Liu, Bowei ^{[1
]}

Li, Meng ^{[2
]}

Cao, Jingui ^{[3
]}

Liu, Ding ^{[4
]}

Wang, Zhigang ^{[5
]}

Wang, Qiongshu ^{[6
]}

Xiao, Pengyun ^{[7
]}

Zhang, Xinling ^{[8
]}

Gao, Yanxin ^{[9
]}

Zeng, Hua ^{[10
]}

Yang, Jing ^{[11
]}

Xu, Xiaoli ^{[12
]}

Huang, Yi ^{[13
]}

Zhang, Qun ^{[14
]}

Zhang, Bo ^{[15
]}

Chen, Wei ^{[16
]}

Shi, Jieran ^{[17
]}

Fan, Shanhong ^{[18
]}

Zhang, Fuxiang ^{[19
]}

Yang, Jinyan ^{[20
]}

Yang, Huining ^{[21
]}

Ding, Zhaoxia ^{[22
]}

Li, Haifeng ^{[23
]}

Xiao, Sha ^{[24
]}

Ran, Suping ^{[25
]}

Zhai, Hongyan ^{[26
]}

Wang, Fang ^{[27
]}

Xing, Yubin ^{[1
]}

Suo, Jijiang ^{[1
]}

Liu, Yunxi ^{[1
]}

机构：

[1] Chinese Peoples Liberat Army Gen Hosp, Dept Infect Management & Dis Control, 28 Fuxing Rd, Beijing 100853, Peoples R China

[2] Chinese Peoples Liberat Army Gen Hosp, Dept Hematol, Beijing, Peoples R China

[3] Air Force Gen Hosp, Dept Infect Control, Beijing, Peoples R China

[4] Daping Hosp, Dept Infect Control, Chongqing, Peoples R China

[5] Army Gen Hosp, Dept Infect Control, Beijing, Peoples R China

[6] Wuhan Gen Hosp, Dept Infect Control, Wuhan, Hubei, Peoples R China

[7] Jinan Gen Hosp, Dept Dis Prevent & Control, Jinan, Shandong, Peoples R China

[8] Lanzhou Gen Hosp, Dept Infect Control, Lanzhou, Gansu, Peoples R China

[9] Urumqi Gen Hosp, Dept Dis Prevent & Control, Urumqi, Peoples R China

[10] Fuzhou Gen Hosp, Dept Infect Control, Fuzhou, Fujian, Peoples R China

[11] ShenYang Gen Hosp, Dept Infect Control, Shenyang, Liaoning, Peoples R China

[12] Nanjing Gen Hosp, Dept Infect Control, Nanjing, Jiangsu, Peoples R China

[13] Changhai Hosp, Dept Infect Management, Shanghai, Peoples R China

[14] Changzheng Hosp, Dept Infect Management, Shanghai, Peoples R China

[15] Xinan Hosp, Dept Infect Control, Chongqing, Peoples R China

[16] Xinqiao Hosp, Dept Infect Control, Chongqing, Peoples R China

[17] Xijing Hosp, Dept Infect Control, Xian, Shaanxi, Peoples R China

[18] Tangdu Hosp, Dept Infect Control, Xian, Shaanxi, Peoples R China

[19] Gen Hosp PLA Rocket Force, Dept Infect Control, Beijing, Peoples R China

[20] Hainan Hosp, Dept Infect Management & Dis Control, Sanya, Peoples R China

[21] Armed Police Gen Hosp, Dept Infect Control, Beijing, Peoples R China

[22] 81 Hosp PLA, Dept Infect Control, Nanjing, Jiangsu, Peoples R China

[23] 202 Hosp PLA, Dept Infect Control, Shenyang, Liaoning, Peoples R China

[24] 211 Hosp PLA, Dept Infect Control, Haerbin, Peoples R China

[25] 306 Hosp PLA, Dept Infect Control, Beijing, Peoples R China

[26] 307 Hosp PLA, Dept Infect Control, Beijing, Peoples R China

[27] 309 Hosp PLA, Dept Infect Control, Beijing, Peoples R China

来源：

BMC INFECTIOUS DISEASES | 2019年 / 19卷 / 1期

基金：

国家重点研发计划;

关键词：

Surgical site infection; Radical resection of colon carcinoma; Radical resection of rectal carcinoma; Prospective surveillance; Multicenter study; COLORECTAL SURGERY;

D O I：

10.1186/s12879-019-4064-6

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

BackgroundColorectal surgery is associated with high rates of surgical site infection (SSI). We investigated SSI in radical resection of colon or rectal carcinoma and its epidemiological distribution in 26 hospitals in China.MethodsWe conducted prospective surveillance of patients who underwent radical resection of colon or rectal carcinoma in 26 selected hospitals from January 2015 to June 2016.An information system monitored all of the surgical inpatients. Infection control professionals observed the inpatients with suspected SSI who had been screened by the system at the bedside. The infection status of the incisions was followed up by telephone 1month after the operation.ResultsIn total, 5729 patients were enrolled for the two operations; SSIs occurred in 206 patients, and the infection rate was 3.60%. The incidence of SSI after radical resection of rectal carcinoma (5.12%; 119/2323) was 2.1 times higher than that after radical resection of colon carcinoma (2.55%; 87/3406) (P<0.0001). Additionally, in the colon versus rectal groups, the rate of superficial incisional SSI was 0.94% versus 2.28% (P<0.0001), the rate of deep incisional SSI was 0.56% versus 1.11% (P=0.018), and the rate of organ space SSI was 1.06% versus 1.72% (P=0.031), respectively. The most common pathogens causing SSIs after radical resection of colon carcinoma were Escherichia coli (21/38) and Pseudomonas aeruginosa (5/38). Escherichia coli (24/65) and Enterococcus spp. (14/65) were the two most common pathogens in the rectal group. The multivariate logistic regression analysis showed that only the operating time and number of hospital beds were common independent risk factors for SSIs after the two types of surgery.ConclusionThis multicenter study showed that there were significant differences in the incidence of SSIs, three types of SSIs, and some risk factors between radical resection of colon carcinoma and rectal carcinoma.

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