A ratiometric flavone-based fluorescent probe for hypochlorous acid detection with large Stokes shift and long-wavelength emission

被引:36
作者
He, Long [1 ]
Zhang, Yun [1 ]
Xiong, Haiqing [1 ]
Wang, Jingpei [1 ]
Geng, Yani [1 ]
Wang, Benhua [1 ]
Wang, Yangang [3 ]
Yang, Zhaoguang [1 ,2 ]
Song, Xiangzhi [1 ,2 ]
机构
[1] Cent S Univ, Coll Chem & Chem Engn, Changsha 410083, Hunan, Peoples R China
[2] Key Lab Hunan Prov Water Environm & Agr Prod Safe, Changsha 410083, Hunan, Peoples R China
[3] Jinxing Univ, Coll Biol Chem Sci & Engn, Jiaxing 314001, Zhejiang, Peoples R China
基金
中国国家自然科学基金;
关键词
Ratiometric; Flavone-based; Long-wavelength; Large Stokes shift; RED EMISSION; LIVING CELLS; MYELOPEROXIDASE; THIOPHENOL; PRODUCT; LIVE;
D O I
10.1016/j.dyepig.2019.03.029
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
A ratiometric fluorescent probe, FPT, was designed and synthesized for the selective and sensitive detection of hypochlorous acid (HClO) based on a flavone derivative under a single wavelength excitation. The addition of HClO to the solution of FPT induced a distinct fluorescence color change from orange to green. Probe FPT was successfully used to detect and image intracellular HClO in living zebra fish in a ratiometric manner.
引用
收藏
页码:390 / 394
页数:5
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