TiO2 nanoparticles as an effective catalyst for the synthesis of hexahydro-2-quinolinecarboxylic acids derivatives

被引:40
作者
Abdolmohammadi, Shahrzad [1 ]
机构
[1] Islamic Azad Univ, E Tehran Branch, Fac Sci, Dept Chem, Tehran, Iran
关键词
One-pot three-component reaction; Pyrido[2,3-d]pyrimidines; Solvent-free; TiO2; nanoparticles; ONE-POT SYNTHESIS;
D O I
10.1016/j.cclet.2012.06.038
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The one-pot three-component reaction of arylmethylidenepyruvic acids, 1,3-cyclohexandiones and ammonium acetate provides an economical and efficient synthetic route to 5-oxo-4-aryl-1,4,5,6,7,8-hexahydro-2-quinolinecarboxylic acid 4 under solvent-free conditions using a catalytic amount of TiO2 nanoparticles (TiO2 NPs) as an effective heterogeneous catalyst. (C) 2012 Shahrzad Abdolmohammad. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
引用
收藏
页码:1003 / 1006
页数:4
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