Clinical Presentation, Diagnosis, and Pathogenesis of Dementia With Lewy Bodies

被引:0
作者
Hirczy, Siegfried [1 ]
Salinas, Meagen [1 ,2 ,3 ]
机构
[1] Univ Texas Southwestern Med Ctr Dallas, Dept Neurol, Dallas, TX USA
[2] Med Serv Dallas, VA Med Ctr, VA North Texas Hlth Care Syst, Neurol Sect, Dallas, TX USA
[3] Univ Texas Southwestern Med Ctr Dallas, 5323 Harry Hines Blvd, Dallas, TX 75390 USA
关键词
PARKINSONS-DISEASE; ALPHA-SYNUCLEIN; ALZHEIMERS-DISEASE; BODY; FEATURES; STAGE; SPECT;
D O I
10.3928/00485713-20220907-01
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Dementia with Lewy bodies is a neurodegenerative disorder typified by progressive cognitive decline with associated visual hallucinations, fluc-tuations in awareness, parkinsonism, and rapid eye movement sleep behav-ior disorder. The diagnosis can be dif-ficult to make and requires a detailed interview, identification of characteris-tic signs on neurological examination, and diagnostic testing when atypical features are present. This article delves into the salient features of the disorder, highlighting the neuropsychiatric spec-trum of clinical manifestations, emerg-ing disease biomarkers, and the role of ancillary studies in the diagnosis. [Psy-chiatr Ann. 2022;52(10):398-403.]
引用
收藏
页码:398 / 403
页数:6
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