Early Language Profiles in Infants at High-Risk for Autism Spectrum Disorders

被引：70

作者：

Hudry, Kristelle ^{[1
]}

Chandler, Susie ^{[2
]}

Bedford, Rachael ^{[3
]}

Pasco, Greg ^{[2
]}

Gliga, Teodora ^{[4
]}

Elsabbagh, Mayada ^{[4
,5
]}

Johnson, Mark H. ^{[4
]}

Charman, Tony ^{[2
]}

机构：

[1] La Trobe Univ, Sch Psychol Sci, Olga Tennison Autism Res Ctr, Melbourne, Vic 3086, Australia

[2] Kings Coll London, Inst Psychiat, Dept Psychol, London WC2R 2LS, England

[3] Kings Coll London, Inst Psychiat, Dept Biostat, London WC2R 2LS, England

[4] Univ London, Ctr Brain & Cognit Dev, London, England

[5] McGill Univ, Dept Psychiat, Montreal, PQ, Canada

来源：

JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS | 2014年 / 44卷 / 01期

基金：

英国医学研究理事会;

关键词：

Autism spectrum disorder; Broader autism phenotype; High-risk siblings; Receptive language; Expressive language; Language profiles; COMMUNICATIVE DEVELOPMENT; CHILDREN; PRESCHOOLERS; VOCABULARY; TODDLERS;

D O I：

10.1007/s10803-013-1861-4

中图分类号：

B844 [发展心理学（人类心理学）];

学科分类号：

040202 ;

摘要：

Many preschoolers with autism spectrum disorders (ASD) present relative lack of receptive advantage over concurrent expressive language. Such profile emergence was investigated longitudinally in 54 infants at high-risk (HR) for ASD and 50 low-risk controls, with three language measures taken across four visits (around 7, 14, 24, 38 months). HR infants presented three outcome subgroups: ASD, other atypicality, and typical development. Reduced receptive vocabulary advantage was observed in HR infants by 14 months, but was maintained to 24 months only in ASD/other atypicality outcome subgroups while typically-developing HR infants regained a more normative profile. Few group differences appeared on a direct assessment of language and parent-reported functional communication. Processes of early development toward ASD outcome and in intermediate phenotypes are discussed.

引用

页码：154 / 167

页数：14

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