SiO2-OSO3H nanoparticles: an efficient, versatile and new reagent for the one-pot synthesis of 2-amino-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carbonitrile derivatives in water, a green protocol

被引:16
作者
Sadeghi, Bahareh [1 ]
Nezhad, Parinaz Farokhi [1 ]
Hashemian, Saeedeh [1 ]
机构
[1] Islamic Azad Univ, Dept Chem, Yazd Branch, Yazd, Iran
关键词
nano-silica sulfuric acid; solid acid; kojic acid; malononitrile; green chemistry; one-pot synthesis; ORGANIC-REACTIONS;
D O I
10.3184/174751914X13866053657371
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
In a one-pot three-component reaction, an aromatic or aliphatic aldehyde, malononitrile and 5-hydroxy-2-hydroxymethyl-4H-pyran-4-one were condensed for the synthesis of 2-amino-8-oxo-4,8-dihydropyrano[ 3,2-b]pyran-3-carbonitrile derivatives in the presence of nano-silica sulfuric acid (SiO2-OSO3H nanoparticles) in improved yields. The catalyst is recoverable by simple filtration and can be used in the subsequent reactions.
引用
收藏
页码:54 / 57
页数:4
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