Impact of diabetes on inpatient mortality and length of stay for elderly patients presenting with fracture of the proximal femur
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作者:
Nirantharakumar, K.
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Univ Birmingham, Birmingham B15 2TT, W Midlands, England
Univ Hosp Birmingham, ePrescribing Res Team, Birmingham, W Midlands, EnglandUniv Birmingham, Birmingham B15 2TT, W Midlands, England
Nirantharakumar, K.
[1
,2
]
Toulis, K. A.
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Univ Birmingham, Birmingham B15 2TT, W Midlands, England
Univ Hosp Birmingham, Ctr Endocrinol Diabet & Metab, Birmingham, W Midlands, EnglandUniv Birmingham, Birmingham B15 2TT, W Midlands, England
Toulis, K. A.
[1
,3
]
Wijesinghe, H.
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Univ Birmingham, Birmingham B15 2TT, W Midlands, EnglandUniv Birmingham, Birmingham B15 2TT, W Midlands, England
Wijesinghe, H.
[1
]
Mastan, M. S.
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Univ Birmingham, Birmingham B15 2TT, W Midlands, EnglandUniv Birmingham, Birmingham B15 2TT, W Midlands, England
Mastan, M. S.
[1
]
Srikantharajah, M.
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Univ Birmingham, Birmingham B15 2TT, W Midlands, EnglandUniv Birmingham, Birmingham B15 2TT, W Midlands, England
Srikantharajah, M.
[1
]
Bhatta, S.
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Univ Birmingham, Birmingham B15 2TT, W Midlands, EnglandUniv Birmingham, Birmingham B15 2TT, W Midlands, England
Bhatta, S.
[1
]
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Marshall, T.
[1
]
Coleman, J. J.
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Univ Hosp Birmingham, ePrescribing Res Team, Birmingham, W Midlands, England
Univ Birmingham, Sch Clin & Expt Med, Birmingham B15 2TT, W Midlands, EnglandUniv Birmingham, Birmingham B15 2TT, W Midlands, England
Coleman, J. J.
[2
,4
]
机构:
[1] Univ Birmingham, Birmingham B15 2TT, W Midlands, England
[2] Univ Hosp Birmingham, ePrescribing Res Team, Birmingham, W Midlands, England
[3] Univ Hosp Birmingham, Ctr Endocrinol Diabet & Metab, Birmingham, W Midlands, England
[4] Univ Birmingham, Sch Clin & Expt Med, Birmingham B15 2TT, W Midlands, England
Introduction: Osteoporosis-related fractures of the proximal femur cause significant morbidity and result in an economic burden on societies. It remains debatable whether diabetic patients with proximal fracture of the femur demonstrate poorer outcomes in terms of hospital stay and mortality compared to non-diabetic controls. Methods: All patients over 65 years old admitted to the University Hospital Birmingham during 2007-2010 with a diagnosis of a fracture of the proximal femur (total 1468 including 197 patients with diabetes) were analysed. Eligibility and case definitions were ascertained using electronic records. Multivariate analyses were conducted to control for the confounding effect of covariates, which may be associated with the outcomes of interest on the basis of biological plausibility and known risks. Results: In-patient mortality was estimated at 14.2% and 12% for the diabetic and non-diabetic patients respectively. Diabetes was not found to be a significant predictor of in-patient mortality, before and after adjustment for the covariates [Adjusted odds ratio 1.01 (95% CI 0.62-1.65)], in contrast to advancing age, male gender, co-morbidity score, low albumin and high creatinine concentrations. Similarly, median length of stay was greater in the diabetes patients, yet only by a day (20 versus 19 days). This was not statistically significant in either the unadjusted (p = 0.17) or in the multivariate analysis (p = 0.06). Conclusions: Diabetic patients admitted with fracture of the proximal femur did not demonstrate significantly poorer outcomes in terms of in-patient mortality and length of stay compared to non-diabetic patients. (C) 2013 Elsevier Inc. All rights reserved.
机构:
Univ Med & Dent New Jersey, Dept Orthopaed, New Jersey Med Sch, Newark, NJ 07103 USAUniv Med & Dent New Jersey, Dept Orthopaed, New Jersey Med Sch, Newark, NJ 07103 USA
Gandhi, A
Beam, HA
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Univ Med & Dent New Jersey, Dept Orthopaed, New Jersey Med Sch, Newark, NJ 07103 USAUniv Med & Dent New Jersey, Dept Orthopaed, New Jersey Med Sch, Newark, NJ 07103 USA
Beam, HA
O'Connor, JP
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Univ Med & Dent New Jersey, Dept Orthopaed, New Jersey Med Sch, Newark, NJ 07103 USAUniv Med & Dent New Jersey, Dept Orthopaed, New Jersey Med Sch, Newark, NJ 07103 USA
O'Connor, JP
Parsons, JR
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Univ Med & Dent New Jersey, Dept Orthopaed, New Jersey Med Sch, Newark, NJ 07103 USAUniv Med & Dent New Jersey, Dept Orthopaed, New Jersey Med Sch, Newark, NJ 07103 USA
Parsons, JR
Lin, SS
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Univ Med & Dent New Jersey, Dept Orthopaed, New Jersey Med Sch, Newark, NJ 07103 USAUniv Med & Dent New Jersey, Dept Orthopaed, New Jersey Med Sch, Newark, NJ 07103 USA
机构:
Catholic Univ Korea, St Pauls Hosp, Dept Internal Med, Div Endocrinol & Metab, Seoul 130709, South Korea
Catholic Univ Korea, Coll Med, Dept Internal Med, Seoul 130709, South KoreaCatholic Univ Korea, St Pauls Hosp, Dept Internal Med, Div Endocrinol & Metab, Seoul 130709, South Korea
Kim, Ji-Hyun
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Jung, Mi-Hyang
Lee, Jung-Min
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Catholic Univ Korea, St Pauls Hosp, Dept Internal Med, Div Endocrinol & Metab, Seoul 130709, South Korea
Catholic Univ Korea, Coll Med, Dept Internal Med, Seoul 130709, South KoreaCatholic Univ Korea, St Pauls Hosp, Dept Internal Med, Div Endocrinol & Metab, Seoul 130709, South Korea
Lee, Jung-Min
Son, Hyun-Shik
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Catholic Univ Korea, St Pauls Hosp, Dept Internal Med, Div Endocrinol & Metab, Seoul 130709, South Korea
Catholic Univ Korea, Coll Med, Dept Internal Med, Seoul 130709, South KoreaCatholic Univ Korea, St Pauls Hosp, Dept Internal Med, Div Endocrinol & Metab, Seoul 130709, South Korea
Son, Hyun-Shik
Cha, Bong-Yun
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Catholic Univ Korea, St Pauls Hosp, Dept Internal Med, Div Endocrinol & Metab, Seoul 130709, South Korea
Catholic Univ Korea, Coll Med, Dept Internal Med, Seoul 130709, South KoreaCatholic Univ Korea, St Pauls Hosp, Dept Internal Med, Div Endocrinol & Metab, Seoul 130709, South Korea
Cha, Bong-Yun
Chang, Sang-Ah
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Catholic Univ Korea, St Pauls Hosp, Dept Internal Med, Div Endocrinol & Metab, Seoul 130709, South Korea
Catholic Univ Korea, Coll Med, Dept Internal Med, Seoul 130709, South KoreaCatholic Univ Korea, St Pauls Hosp, Dept Internal Med, Div Endocrinol & Metab, Seoul 130709, South Korea
机构:
Univ Arkansas Med Sci, Div Endocrinol & Metab, Ctr Osteoporosis & Metab Bone Dis, Little Rock, AR 72205 USA
Cent Arkansas Vet Healthcare Syst, Little Rock, AR 72205 USAUniv Arkansas Med Sci, Div Endocrinol & Metab, Ctr Osteoporosis & Metab Bone Dis, Little Rock, AR 72205 USA
机构:
Univ Med & Dent New Jersey, Dept Orthopaed, New Jersey Med Sch, Newark, NJ 07103 USAUniv Med & Dent New Jersey, Dept Orthopaed, New Jersey Med Sch, Newark, NJ 07103 USA
Gandhi, A
Beam, HA
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Univ Med & Dent New Jersey, Dept Orthopaed, New Jersey Med Sch, Newark, NJ 07103 USAUniv Med & Dent New Jersey, Dept Orthopaed, New Jersey Med Sch, Newark, NJ 07103 USA
Beam, HA
O'Connor, JP
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Univ Med & Dent New Jersey, Dept Orthopaed, New Jersey Med Sch, Newark, NJ 07103 USAUniv Med & Dent New Jersey, Dept Orthopaed, New Jersey Med Sch, Newark, NJ 07103 USA
O'Connor, JP
Parsons, JR
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Univ Med & Dent New Jersey, Dept Orthopaed, New Jersey Med Sch, Newark, NJ 07103 USAUniv Med & Dent New Jersey, Dept Orthopaed, New Jersey Med Sch, Newark, NJ 07103 USA
Parsons, JR
Lin, SS
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Univ Med & Dent New Jersey, Dept Orthopaed, New Jersey Med Sch, Newark, NJ 07103 USAUniv Med & Dent New Jersey, Dept Orthopaed, New Jersey Med Sch, Newark, NJ 07103 USA
机构:
Catholic Univ Korea, St Pauls Hosp, Dept Internal Med, Div Endocrinol & Metab, Seoul 130709, South Korea
Catholic Univ Korea, Coll Med, Dept Internal Med, Seoul 130709, South KoreaCatholic Univ Korea, St Pauls Hosp, Dept Internal Med, Div Endocrinol & Metab, Seoul 130709, South Korea
Kim, Ji-Hyun
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Jung, Mi-Hyang
Lee, Jung-Min
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h-index: 0
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Catholic Univ Korea, St Pauls Hosp, Dept Internal Med, Div Endocrinol & Metab, Seoul 130709, South Korea
Catholic Univ Korea, Coll Med, Dept Internal Med, Seoul 130709, South KoreaCatholic Univ Korea, St Pauls Hosp, Dept Internal Med, Div Endocrinol & Metab, Seoul 130709, South Korea
Lee, Jung-Min
Son, Hyun-Shik
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Catholic Univ Korea, St Pauls Hosp, Dept Internal Med, Div Endocrinol & Metab, Seoul 130709, South Korea
Catholic Univ Korea, Coll Med, Dept Internal Med, Seoul 130709, South KoreaCatholic Univ Korea, St Pauls Hosp, Dept Internal Med, Div Endocrinol & Metab, Seoul 130709, South Korea
Son, Hyun-Shik
Cha, Bong-Yun
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Catholic Univ Korea, St Pauls Hosp, Dept Internal Med, Div Endocrinol & Metab, Seoul 130709, South Korea
Catholic Univ Korea, Coll Med, Dept Internal Med, Seoul 130709, South KoreaCatholic Univ Korea, St Pauls Hosp, Dept Internal Med, Div Endocrinol & Metab, Seoul 130709, South Korea
Cha, Bong-Yun
Chang, Sang-Ah
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Catholic Univ Korea, St Pauls Hosp, Dept Internal Med, Div Endocrinol & Metab, Seoul 130709, South Korea
Catholic Univ Korea, Coll Med, Dept Internal Med, Seoul 130709, South KoreaCatholic Univ Korea, St Pauls Hosp, Dept Internal Med, Div Endocrinol & Metab, Seoul 130709, South Korea
机构:
Univ Arkansas Med Sci, Div Endocrinol & Metab, Ctr Osteoporosis & Metab Bone Dis, Little Rock, AR 72205 USA
Cent Arkansas Vet Healthcare Syst, Little Rock, AR 72205 USAUniv Arkansas Med Sci, Div Endocrinol & Metab, Ctr Osteoporosis & Metab Bone Dis, Little Rock, AR 72205 USA