I2-promoted direct one-pot synthesis of 2-aryl-3-(pyridine-2-ylamino)imidazo[1,2-a]pyridines from aromatic ketones and 2-aminopyridines

被引：72

作者：

Fei, Zhuan ^{[1
]}

Zhu, Yan-ping ^{[1
]}

Liu, Mei-cai ^{[1
]}

Jia, Feng-cheng ^{[1
]}

Wu, An-xin ^{[1
]}

机构：

[1] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China

来源：

TETRAHEDRON LETTERS | 2013年 / 54卷 / 10期

基金：

中国国家自然科学基金;

关键词：

Aromatic ketones; One-pot; Imidazo[1,2-a]pyridines; Heterocyclization; OXIDATIVE CYCLIZATION; FACILE SYNTHESIS; EFFICIENT; 2-ACYLBENZOTHIAZOLES; AMINOPYRIDINES; AMINATION; DISCOVERY; ZOLPIDEM; ESTERS;

D O I：

10.1016/j.tetlet.2012.12.072

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An I-2-promoted one-pot protocol was proposed for the synthesis of 2-aryl-3-(pyridine-2-ylamino)imidazo[1,2-a]pyridines from aromatic ketones and 2-aminopyridines. The present reaction proceeded well in the presence of I-2 in DMSO, and it avoided the requirement of any metal, base, and ligand. (C) 2013 Elsevier Ltd. All rights reserved.

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页码：1222 / 1226

页数：5

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