New interspecific hybrid Prunus rootstocks have been developed in Europe for use in calcareous soils and in replant conditions. A trial was set up in the Controlled Denomination "Peach of Calanda" growing area (NE Spain) to assess the performance of the late-ripening clingstone peach 'Jesca' on six different rootstocks, GF-677, Barrier, Cadaman-Avimag, Felinem, Garnem and Monegro, just one year after uprooting a 20-year-old peach orchard. All grew well in under these replant and climate conditions. Barrier and GF-677 induced the greatest precocity and had greater early yields than Garnem. Tree vigor was strongly affected by rootstock and replanting conditions, with Cadaman and Barrier showing the lowest vigor. However, productivity indexes of these two rootstocks were higher than for GF-677, the reference rootstock in Europe. Similar productivity indexes were obtained for Felinem and GF-677. Fruit size was not influenced by the rootstock, except for GF-677, which had significantly smaller fruit size. The chlorophyll content index (Spad) in leaves of 'Jesca' was higher on GF-677 and Cadaman than on Garnem. These differences in Spad index may imply less susceptibility to iron chlorosis in cultivars grafted on GF-677 and Cadaman. Our results show that in a replant site with calcareous soil and without nematode problems, Barrier and Cadaman induced less tree vigor, larger fruit size and higher productivity than GF-677 with 'Jesca' cling peach. Trees on Felinem also showed an acceptable behavior in these conditions.