Relay photocatalytic cascade reactions: synthesis of indolo[2,1-a] isoquinoline derivatives via double C(sp3)-H bond functionalization

被引：20

作者：

Cheng, Jian ^{[1
]}

Xie, Jin ^{[1
]}

Zhu, Chengjian ^{[1
,2
]}

机构：

[1] Nanjing Univ, Sch Chem & Chem Engn, Jiangsu Key Lab Adv Organ Mat, State Key Lab Coordinat Chem, Nanjing 210023, Jiangsu, Peoples R China

[2] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2018年 / 54卷 / 13期

基金：

中国国家自然科学基金;

关键词：

LIGHT PHOTOREDOX CATALYSIS; VISIBLE-LIGHT; ALKENES; TRIFLUOROMETHYLATION; CYCLOPROPANATION; DISCOVERY; RADICALS; STRATEGY;

D O I：

10.1039/c7cc09820k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A relay photoredox catalysis strategy concomitant with [1,5] hydrogen atom transfer has been applied in the construction of a biologically important indolo[2,1-a] isoquinoline framework via a cascade reaction. This reaction enables double C(sp(3))-H bond functionalization and formation of two carbon-carbon double bonds from readily available starting materials in an efficient and step-economical manner.

引用

页码：1655 / 1658

页数：4

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