Central nervous system manifestations of neonatal lupus: a systematic review

被引：21

作者：

Chen, C. C. ^{[1
]}

Lin, K-L ^{[2
,3
]}

Chen, C-L ^{[1
]}

Wong, A. May-Kuen ^{[1
]}

Huang, J-L ^{[3
,4
]}

机构：

[1] Chang Gung Mem Hosp, Dept Phys Med & Rehabil, Tao Yuan, Taiwan

[2] Chang Gung Childrens Hosp, Div Pediat Neurol, Tao Yuan, Taiwan

[3] Chang Gung Univ, Coll Med, Tao Yuan, Taiwan

[4] Chang Gung Childrens Hosp, Tao Yuan, Taiwan

来源：

LUPUS | 2013年 / 22卷 / 14期

关键词：

Neonate; neonatal lupus; central nervous system; autoimmune disease; ERYTHEMATOSUS; HYDROCEPHALUS; AUTOANTIBODIES; VASCULOPATHY; INVOLVEMENT; EXPRESSION; SIBLINGS; CHILDREN;

D O I：

10.1177/0961203313509294

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Neonatal lupus is a rare and acquired autoimmune disease. Central nervous system abnormalities are potential manifestations in neonatal lupus. Through a systematic literature review, we analyzed the clinical features of previously reported neonatal lupus cases where central nervous system abnormalities had been identified. Most reported neonatal lupus patients with central nervous system involvement were neuroimaging-determined and asymptomatic. Only seven neonatal lupus cases were identified as having a symptomatic central nervous system abnormality which caused physical disability or required neurosurgery. A high percentage of these neurosymptomatic neonatal lupus patients had experienced a transient cutaneous skin rash and had no maternal history of autoimmune disease before pregnancy.

引用

页码：1484 / 1488

页数：5

共 24 条

[1] Frequency of neuro-psychiatric dysfunction in anti-SSA/SSB exposed children with and without neonatal lupus [J].

Askanase, A. D. ;

Izmirly, P. M. ;

Katholi, M. ;

Mumtaz, J. ;

Buyon, J. P. .

LUPUS, 2010, 19 (03) :300-306

[2] Neonatal lupus erythematosus and neurologic involvement:: an incidental association? [J].

Besson-Léaud, L ;

Fontan, D ;

Billeaud, C ;

Sandler, B .

ARCHIVES DE PEDIATRIE, 2002, 9 (05) :503-505

[3] Hydrocephalus and macrocephaly: New manifestations of neonatal lupus erythematosus [J].

Boros, Christina A. ;

Spence, Dawn ;

Blaser, Susan ;

Silverman, Earl D. .

ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH, 2007, 57 (02) :261-266

[4] NEONATAL LUPUS-ERYTHEMATOSUS WITH PERSISTENT TELANGIECTASIA AND SPASTIC PARAPARESIS [J].

BOURKE, JF ;

BURNS, DA .

CLINICAL AND EXPERIMENTAL DERMATOLOGY, 1993, 18 (03) :271-273

[5] Pregnancy Outcomes in Patients with Autoimmune Diseases and Anti-Ro/SSA Antibodies [J].

Brucato, Antonio ;

Cimaz, Rolando ;

Caporali, Roberto ;

Ramoni, Veronique ;

Buyon, Jill .

CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY, 2011, 40 (01) :27-41

[6]

Burch Joanna M, 2002, Dermatol Nurs, V14, P157

[7] Central nervous system vasculopathy in neonatal lupus erythematosus [J].

Cabanas, F ;

Pellicer, A ;

Valverde, E ;

Morales, C ;

Quero, J .

PEDIATRIC NEUROLOGY, 1996, 15 (02) :124-126

[8] Neonatal autoimmune diseases: A critical review [J].

Chang, Christopher .

JOURNAL OF AUTOIMMUNITY, 2012, 38 (2-3) :J223-J238

[9] Neonatal lupus complicated by hemorrhagic stroke [J].

Chen, C. C. ;

Huang, J. L. ;

Hsu, J. F. ;

Chung, C. Y. ;

Lin, K. L. .

LUPUS, 2012, 21 (14) :1582-1585

[10] Incidence and spectrum of neonatal lupus erythematosus: A prospective study of infants born to mothers with anti-Ro autoantibodies [J].

Cimaz, R ;

Spence, DL ;

Hornberger, L ;

Silverman, ED .

JOURNAL OF PEDIATRICS, 2003, 142 (06) :678-683

← 1 2 3 →