Tetrahydrobostrycin and 1-deoxytetrahydrobostrycin, two new hexahydroanthrone derivatives, from a marine-derived fungus Aspergillus sp.

被引：27
作者：
Xu, Jinzhong [1 ]
Nakazawa, Takahiro [1 ]
Ukai, Kazuyo [1 ]
Kobayashi, Hisayoshi [2 ]
Mangindaan, Remy E. P. [3 ]
Wewengkang, Defny S. [3 ]
Rotinsulu, Henki [3 ]
Namikoshi, Michio [1 ]
机构：
[1] Tohoku Pharmaceut Univ, Aoba Ku, Sendai, Miyagi 9818558, Japan
[2] Univ Tokyo, Inst Mol & Cellular Biosci, Bunkyo Ku, Tokyo 1130032, Japan
[3] Sam Ratulangi Univ, Fac Fisheries & Marine Sci, Manado 95115, Indonesia
来源：
JOURNAL OF ANTIBIOTICS | 2008年 / 61卷 / 07期
关键词：
marine-derived fungus; Aspergillus sp; tetrahydrobostrycin; 1-deoxytetrahydrobostrycin; hexahydroanthrone; bostrycin; abscisic acid;
D O I：
10.1038/ja.2008.57
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Two new hexahydroanthrones, tetrahydrobostrycin. (1) and 1-deoxytetrahydrobostrycin (2), were isolated from a marine-derived fungus Aspergillus sp. strain 05F16 collected at the coral reef of Manado, Indonesia, together with bostrycin and abscisic acid. The structures of new compounds were determined on the basis of their spectral data. Compound I showed weak antibacterial activity against Staphylococcus aureus and Escherichia coli and 2 against S. aureus.
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收藏
页码：415 / 419
页数：5
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