Long-term survival with complete remission after hepatic arterial infusion chemotherapy for liver metastasis from gastric cancer: a case report

被引：5

作者：

Toyokawa, Takahiro ^{[1
]}

Ohira, Masaichi ^{[1
]}

Sakurai, Katsunobu ^{[1
]}

Amano, Ryosuke ^{[1
]}

Kubo, Naoshi ^{[1
]}

Tanaka, Hiroaki ^{[1
]}

Muguruma, Kazuya ^{[1
]}

Hirakawa, Kosei ^{[1
]}

机构：

[1] Osaka City Univ, Dept Surg Oncol, Grad Sch Med, Abeno Ku, Osaka 5458585, Japan

来源：

WORLD JOURNAL OF SURGICAL ONCOLOGY | 2015年 / 13卷

关键词：

Gastric cancer; Hepatic arterial infusion chemotherapy; Liver metastasis; CURATIVE RESECTION; RECURRENCE; STOMACH; S-1;

D O I：

10.1186/s12957-015-0686-3

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We report a case of long-term survival with complete remission after hepatic arterial infusion chemotherapy (HAIC) for liver metastasis from gastric cancer. A 62-year-old man underwent radical distal gastrectomy with D2 lymphadenectomy for an advanced gastric cancer. Solitary liver metastasis in the S2/3 segment was detected 26 months after initial surgery. The patient underwent HAIC with systemic chemotherapy. Serum CEA levels rapidly decreased, and CT scan showed disappearance of the tumor with complete clinical response 8 months after HAIC. HAIC was performed 83 times in total, until the hepatic artery proper was adequately obstructed. No severe adverse effects were observed during HAIC treatment. The patient is still disease-free without further chemotherapy more than 12 years after HAIC. Our experience suggests that HAIC should be considered as a treatment option in patients with resectable liver metastasis from gastric cancer. However, further studies are needed to verify the validity of HAIC for resectable liver metastasis from gastric cancer.

引用

页数：5

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